The Longterm Risk of Advanced Colorectal Neoplasia After Colonoscopy - A Population-based Cohort Study in Hong Kong

NCT ID: NCT04815525

Last Updated: 2024-02-09

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

RECRUITING

Total Enrollment

5000 participants

Study Classification

OBSERVATIONAL

Study Start Date

2023-01-01

Study Completion Date

2026-12-31

Brief Summary

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The primary objective of this study is to analyze the 15-year cumulative incidence of advanced colorectal neoplasia and CRC-related mortality after the index colonoscopy.

Detailed Description

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This is a territory-wide retrospective observational cohort study using the Clinical Data Analysis and Reporting System (CDARS). We will identify patients from CDARS with colonoscopy performed from 1 January 2000 to 31 October 2020. Other relevant diagnoses, procedures, concomitant drugs, laboratory parameters and pathology results will be retrieved and studied.

Conditions

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Colorectal Neoplasia Colorectal Cancer

Study Design

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Observational Model Type

COHORT

Study Time Perspective

RETROSPECTIVE

Study Groups

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Normal finding

Colonoscopy finding normal

No interventions assigned to this group

Hyperplastic polyps

Colonoscopy finding of hyperplastic polyps

No interventions assigned to this group

Low-risk adenomas

Colonoscopy finding of low-risk adenomas

No interventions assigned to this group

High-risk adenomas

Colonoscopy finding of high-risk adenomas

No interventions assigned to this group

Eligibility Criteria

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Inclusion Criteria

1\. All patients with colonoscopy performed in HA hospitals during the study period would be eligible for screening.

Exclusion Criteria

1\. Patients with documented personal history of colorectal cancers before the study period would be excluded.
Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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Chinese University of Hong Kong

OTHER

Sponsor Role lead

Responsible Party

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Louis Ho Shing Lau

Resident Specialist

Responsibility Role PRINCIPAL_INVESTIGATOR

Locations

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Prince of Wales Hospital

Shatin, New Territories, Hong Kong

Site Status RECRUITING

Countries

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Hong Kong

Central Contacts

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Felix Sia

Role: CONTACT

+85226370428

Thomas Lam

Role: CONTACT

+85226370428

Other Identifiers

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2020.597

Identifier Type: -

Identifier Source: org_study_id

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