Effects of Different Deflation Methods on Coughing Response and Hemodynamics During Extubation

NCT ID: NCT05647395

Last Updated: 2022-12-12

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Clinical Phase

NA

Total Enrollment

90 participants

Study Classification

INTERVENTIONAL

Study Start Date

2022-10-01

Study Completion Date

2024-07-30

Brief Summary

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Patients with endotracheal intubation and general anesthesia often have severe choking and hemodynamic fluctuations during the extubation period, which increases the risk of cerebrovascular accident, arrhythmia, incision bleeding and so on . This study aimed to observe the effects of different methods of deflating of endotracheal tube cuffs on cough response and hemodynamics during periextubation in patients undergoing general anesthesia surgery.

Detailed Description

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Conditions

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Deflating Method

Keywords

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Deflating method Extubation phase Coughing reaction

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

PREVENTION

Blinding Strategy

TRIPLE

Participants Investigators Outcome Assessors

Study Groups

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Slowly and evenly draw the gas in the cuff

Group Type EXPERIMENTAL

Tracheal tube cuffs differ in deflation

Intervention Type BEHAVIORAL

When removing the endotracheal tube, the gas in the cuff is drawn at a uniform and slow pace

One-time aspiration of tracheal catheter cuff gas

Group Type NO_INTERVENTION

No interventions assigned to this group

Interventions

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Tracheal tube cuffs differ in deflation

When removing the endotracheal tube, the gas in the cuff is drawn at a uniform and slow pace

Intervention Type BEHAVIORAL

Eligibility Criteria

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Inclusion Criteria

1. Elective endotracheal intubation under general anesthesia.
2. Operation time \< 3 h.
3. ASA grade I or II.
4. Age 18\~65 years old.

Exclusion Criteria

1. Throat and neck surgery.
2. Those assessed to have a high risk of reflux aspiration.
3. Difficulty intubation.
4. History of snoring before surgery.
5. Recent respiratory illness such as chronic cough.
6. Previous airway hyperresponsiveness, such as asthma.
7. recent use of cough suppressants.
8. Patients with severe heart, liver and kidney diseases.
Minimum Eligible Age

18 Years

Maximum Eligible Age

65 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Zhuan Zhang

OTHER

Sponsor Role lead

Responsible Party

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Zhuan Zhang

Principal Investigator

Responsibility Role SPONSOR_INVESTIGATOR

Locations

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the Affiliated Hospital of Yangzhou University, Yangzhou University

Yangzhou, Jiangsu, China

Site Status RECRUITING

Countries

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China

Central Contacts

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Zhuan Zhang

Role: CONTACT

Phone: +8615062791355

Email: [email protected]

Facility Contacts

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Zhuan Zhang, professor

Role: primary

Other Identifiers

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20221121

Identifier Type: -

Identifier Source: org_study_id