Exclusive Breastfeeding Improves Puerperal Glucose Metabolism in Pregnant Women With Gestational Diabetes Mellitus and Links to Lipids Composition

NCT ID: NCT05629403

Last Updated: 2022-11-29

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

84 participants

Study Classification

OBSERVATIONAL

Study Start Date

2021-09-01

Study Completion Date

2022-07-01

Brief Summary

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Breastfeeding could effectively be associated with a lower risk of future type 2 diabetes (T2D) in women with gestational diabetes mellitus (GDM), but the short-term protective impact of puerperal breastfeeding on maternal metabolic recovery of GDM women remains unascertained. The investigators recruited GDM participants at 6-9 weeks postpartum and retrieved clinical diagnoses of GDM from electronic medical records. Feeding patterns were collected via phone calls. Glucose metabolism parameters and lipid profiling were performed on fasting plasma samples collected from patients 6-9 weeks postpartum (20 breastfeeding cases vs. 15 formula feeding cases).

Detailed Description

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Conditions

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Gestational Diabetes Breast Feeding Lipid Metabolism Disorders

Study Design

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Observational Model Type

CASE_CONTROL

Study Time Perspective

CROSS_SECTIONAL

Study Groups

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exclusive breastfeeding

breastfeeding exclusively

observe

Intervention Type OTHER

no intervention

formula feeding

formula feeding

observe

Intervention Type OTHER

no intervention

Interventions

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observe

no intervention

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

1. 18-35 years old;
2. gestational age greater than 37 weeks;
3. Body Mass Index (BMI) before pregnancy 18.5-28kg/m2;
4. Have normal listening and speaking skills, can communicate, and are willing to participate in this study.

Exclusion Criteria

1. abnormal glucose metabolism or diabetes has been diagnosed before pregnancy;
2. assisted reproduction;
3. GDM patients requiring drug treatment;
4. The use of blood lipid regulation drugs;
5. other pregnancy complications and complications;
6. Suffering from heart, malignant tumor, kidney and other major organ diseases;
7. associated with neurological dysfunction and cognitive impairment;
8. Failure to cooperate with follow-up observers.
Minimum Eligible Age

18 Years

Maximum Eligible Age

35 Years

Eligible Sex

FEMALE

Accepts Healthy Volunteers

No

Sponsors

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Nanjing Medical University

OTHER

Sponsor Role lead

Responsible Party

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Xirong Guo

Professor

Responsibility Role PRINCIPAL_INVESTIGATOR

Locations

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Nanjing Maternal and child Health Care Hospital

Nanjing, Jiangsu, China

Site Status

Countries

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China

Other Identifiers

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NanjingMU2022

Identifier Type: -

Identifier Source: org_study_id

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