Neuropsychiatric Symptoms in Spontaneous Intracerebral Hemorrhage Survivors

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

Get a concise snapshot of the trial, including recruitment status, study phase, enrollment targets, and key timeline milestones.

Recruitment Status

UNKNOWN

Total Enrollment

120 participants

Study Classification

OBSERVATIONAL

Study Start Date

2023-01-01

Study Completion Date

2023-12-31

Brief Summary

Review the sponsor-provided synopsis that highlights what the study is about and why it is being conducted.

Compared to the United Kingdom and the United States, Spontaneous non-traumatic intracerebral hemorrhage (ICH) is more common among people in Taiwan. The prevalence rate of ICH was 14.0% for people aged 36 years or older in Taiwan. Primary ICH originates from the spontaneous rupture of small vessels damaged by chronic hypertension or cerebral amyloid angiopathy (CAA). Emotional disturbances are frequent symptoms in stroke survivors and negatively impact on functional recovery, the patient's quality of life and are distressing for both the patients and their caregivers. Furthermore, the emotional disturbances are associated with impaired cognitive. However, these issues are often unnoticed and most of the studies had been performed in ischemic stroke survivors rather than in patients with ICH.

In this study, we will be recruited participants from National Taiwan University Hospital Bei-Hu branch and National Taiwan University Hospital. We aim to enroll respectively maximum number of 60 patients who had previous spontaneous ICH. Each participant will receive neuropsychiatric assessment, cognitive screening tests, domain-specific cognitive tests, a questionnaire for their quality of life and blood drawing for ApoE genotyping. The main aims of this study include (1) To investigate the prevalence of distinct neuropsychiatric symptoms in ICH survivors (2) To investigate the impact of non-cognitive neuropsychiatric issues on the cognitive functions and quality of life in ICH survivors. Our results may remind clinicians to pay more attention to the early diagnosis and effective management of neuropsychiatric symptoms to improve clinical outcomes.

Related Clinical Trials

Explore similar clinical trials based on study characteristics and research focus.

Time Frequency Analysis of Electrocardiogram and Blood Pressure in Intracranial Hemorrhage Patients

NCT00713375

Subarachnoid Hemorrhage Intracranial Hemorrhages Cerebral Hemorrhage

UNKNOWN

China Research for Severe Spontaneous Intracerebral Hemorrhage（CRISIH）

NCT05975398

Severe Spontaneous Intracranial Hemorrhage Long-term Antiplatelet Treatment Emergency Surgery +1 more

RECRUITING

Multimodal Monitoring in Patients With Spontaneous Intracerebral Hemorrhage

NCT02326571

Cerebral Hemorrhage

COMPLETED

Hidden Impairments During Subarachnoid Haemorrhage Recovery, Description and Evolution of a Newly Described Syndrom

NCT06276517

Intracranial Hemorrhages

NOT_YET_RECRUITING

Impact of Cardiac Blood Flow on Cerebral Blood Flow in Patients With Severe Traumatic Brain Injury

NCT02019810

Severe Traumatic Brain Injury With High Cerebral Pressure

UNKNOWN PHASE2

Detailed Description

Dive into the extended narrative that explains the scientific background, objectives, and procedures in greater depth.

Conditions

See the medical conditions and disease areas that this research is targeting or investigating.

Primary Disease or Condition Being Studied, or Focus of the Study

Study Design

Understand how the trial is structured, including allocation methods, masking strategies, primary purpose, and other design elements.

Observational Model Type

COHORT

Study Time Perspective

RETROSPECTIVE

Interventions

Learn about the drugs, procedures, or behavioral strategies being tested and how they are applied within this trial.

neuropsychiatric symptoms

Intervention Type BEHAVIORAL

Eligibility Criteria

Check the participation requirements, including inclusion and exclusion rules, age limits, and whether healthy volunteers are accepted.

Inclusion Criteria

1. The patient is older than 20-year-old (older than 18-year-old from Jan 1st, 2023) with a past medical history of spontaneous intracerebral hemorrhage.
2. The weight of patient is over 50 Kilograms
3. Patient agrees to participate in the study

Exclusion Criteria

1. Patients who experience acute phase of stroke or neurological disorders, or vision loss and hearing impairment
2. Patient cannot cooperate with the interview including those with aphasia, conscious disturbance or bedridden status

Minimum Eligible Age

20 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No