HYPNOsis in the Management of Atopic Dermatitis in Children and Teenagers

NCT ID: NCT05611346

Last Updated: 2025-09-12

Basic Information

• Recruitment Status: RECRUITING
• Clinical Phase: NA
• Total Enrollment: 32 participants
• Study Classification: INTERVENTIONAL
• Study Start Date: 2024-08-13
• Study Completion Date: 2027-12-31

Brief Summary

Atopic dermatitis (AD) is a chronic inflammatory dermatosis, common in children. It causes pruritus and skin lesions that can have a significant impact on patients' quality of life. AD can be difficult to treat because of its chronicity, demanding local care, corticophobia and the financial cost of non-reimbursed products. Patients are often looking for therapeutic alternatives. Medical hypnosis is a therapeutic alternative via hypnoanalgesia induced by direct suggestions of comfort and skin soothing and via anxiolysis, by working on stress management and self-esteem reinforcement. Four studies are interested in its action in AD and seem to show a reduction in pruritus, skin pain, an improvement in the intensity of atopic dermatitis, sleep, mood and for some a cure of AD. These results are encouraging but limited by the absence of a control group or by the small population included. Therefore, we propose in a first step to evaluate the feasibility of an hypnosis program through a pilot study, designed in the miniature format of a future, larger scale, randomized controlled trial.

Conditions

Dermatitis

Study Design

• Allocation Method: RANDOMIZED
• Intervention Model: PARALLEL
• Primary Study Purpose: SUPPORTIVE_CARE
• Blinding Strategy: NONE

Study Groups

Therapeutic education program

Group Type: NO_INTERVENTION

No interventions assigned to this group

Therapeutic education program and Hypnosis

Group Type: EXPERIMENTAL

Hypnosis

Intervention Type: BEHAVIORAL

The experimental group will receive 2 standardized hypnosis sessions via the "superhero costume" technique performed during this collective therapeutic education program, completed by a reinforcement through the practice of self-hypnosis at home guided by the listening of an audio recording

Interventions

Hypnosis

The experimental group will receive 2 standardized hypnosis sessions via the "superhero costume" technique performed during this collective therapeutic education program, completed by a reinforcement through the practice of self-hypnosis at home guided by the listening of an audio recording

Intervention Type: BEHAVIORAL

Eligibility Criteria

Inclusion Criteria

• Children aged 8 to 17 years
• Understanding french
• Have a clinical diagnosis of mild-to-severe AD with a SCORing Atopic Dermatitis (SCORAD)
• Referred by their referring physician in the Reunionese therapeutic education program for AD provided within the atopy school of the Reunion University Hospital. - Oral consent of the child and of one of the legal representatives collected.

Exclusion Criteria

• Children refusing to participate in the hypnosis session
• Not having the possibility to listen to an audio file,
• Already practicing self-hypnosis for their AD before inclusion,
• Having a contraindication to hypnosis (psychiatric disorders, psychosis)
• Treated by a systemic treatment for their AD.

• Minimum Eligible Age: 8 Years
• Maximum Eligible Age: 17 Years
• Eligible Sex: ALL
• Accepts Healthy Volunteers: No

Sponsors

Centre Hospitalier Universitaire de la Réunion

OTHER

Sponsor Role: lead

Responsible Party

Responsibility Role: SPONSOR

Principal Investigators

Juliette MIQUEL, MD

Role: PRINCIPAL_INVESTIGATOR

CHU de la Réunion

Locations

CHU de la Réunion

Saint-Denis, , Reunion

Site Status: RECRUITING

Countries

Reunion

Central Contacts

Juliette MIQUEL, MD

Role: CONTACT

juliette.miquel@chu-reunion.fr

+262 262 35 90 00

Camille ESPAGNON, MD

Role: CONTACT

camille.espagnon@laposte.net

Facility Contacts

Juliette MIQUEL, MD

Role: primary

juliette.miquel@chu-reunion.fr

Camille ESPAGNON, MD

Role: backup

camille.espagnon@laposte.net

Other Identifiers

2022/CHU/15

Identifier Type: -

Identifier Source: org_study_id