Evaluation of A-1 Cool Cream Efficacy for Treatment Atopic Dermatitis
NCT ID: NCT01174511
Last Updated: 2011-07-06
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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UNKNOWN
PHASE1/PHASE2
30 participants
INTERVENTIONAL
2011-07-31
2012-11-30
Brief Summary
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Initial treatment is based on keeping skin moist and avoiding a flare-provoking stimuli and allergens. The research product A-1 COOL is a skin cream approved by the Israeli Ministry of Health for cooling down of skin irritation. A-1 COOL is rich in herbal medicine ingredients and does not contain steroids.A-1 COOL can be beneficial in Atopic Dermatitis patients due to its following action mechanisms: sealing of the inflamed skin and retention of water, prevention of the itching cycle by keeping the skin moist, disinfection of the skin by the herbal ingredients.
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Detailed Description
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Diagnosis of atopic dermatitis is clinical and depends on the existence of at least two out of the four following criteria: itching, a chronic disease course with exacerbations and remission ,rash with characteristic distribution and shape , atopia of the patient or family by history.
Initial treatment is based on keeping skin moist and avoiding a flare-provoking stimuli and allergens. Topical ointments which grease the skin have shown and reduction of skin inflammation. These products can include active substances such as steroids and anti-inflammatory compounds.
Systemic treatments for atopic dermatitis mainly include steroids and cyclosporine.
The research product A-1 COOL is a skin cream approved by the Israeli Ministry of Health for cooling down of skin irritation. A-1 COOL is rich in herbal medicine ingredients and does not contain steroids.A-1 COOL can be beneficial in Atopic Dermatitis patients due to its following action mechanisms: sealing of the inflamed skin and retention of water, prevention of the itching cycle by keeping the skin moist, disinfection of the skin by the herbal ingredients.
Conditions
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Study Design
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RANDOMIZED
PARALLEL
SUPPORTIVE_CARE
TRIPLE
Study Groups
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A-1 COOL cream
A research product - A-1 COOL cream contain herbal medicine plants basically :
1. WATER PETROLATUM
2. WILD YAM (DIOSCOREA VILLOSA) EXTRACT
3. SORBITAN SESQUIOLEATE
4. CALENDULA OFFICINALIS EXTRACT
5. MINERAL OIL
6. ARNICA MONTANA EXTRACT
7. MICROCRYSTALLINE WAX
8. LICORICE (GLYCYRRHIZA GLABRA) EXTRACT
9. DECYL OLEATE
10. DICOCOYL PENTAERYTHRITYL DISTEARYL CITRATE
11. BEESWAX
12. ALUMINUM STEARATES
A -1 Cool Cream,Vaselin ointment
A- 1 Cool Cream applied to flexural aspects of the upper and lower limb on the one site of patient and placebo (Vaseline ointment) applied to other site of the upper and lower limb in the itch patient. Applying the ointment will be a regular time, twice a day for 5 consecutive days
Vaselin ointment
Using the study as placebo.
A -1 Cool Cream,Vaselin ointment
A- 1 Cool Cream applied to flexural aspects of the upper and lower limb on the one site of patient and placebo (Vaseline ointment) applied to other site of the upper and lower limb in the itch patient. Applying the ointment will be a regular time, twice a day for 5 consecutive days
Interventions
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A -1 Cool Cream,Vaselin ointment
A- 1 Cool Cream applied to flexural aspects of the upper and lower limb on the one site of patient and placebo (Vaseline ointment) applied to other site of the upper and lower limb in the itch patient. Applying the ointment will be a regular time, twice a day for 5 consecutive days
Eligibility Criteria
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Inclusion Criteria
* Hebrew-speaking men and women,
* over 18 years old.
Exclusion Criteria
* patients under the age of 18, pregnant women, no - helpless, soldiers and prisoners,
* patients with atopic dermatitis treated with systemic preparations such as cyclosporine, steroids, antibiotics, methotrexate, biological preparations.
18 Years
ALL
No
Sponsors
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Hadassah Medical Organization
OTHER
Responsible Party
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Hadassah Medical Organization, Jerusalem, Israel
Central Contacts
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Related Links
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Katoh N.Future perspectives in the treatment of atopic dermatitis.
Other Identifiers
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0124-10-HMO-ctil
Identifier Type: -
Identifier Source: org_study_id
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