Renal Perfusion Assessment in the Endovascular Treatment of Renal Artery Stenosis

NCT ID: NCT05603221

Last Updated: 2022-11-02

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Total Enrollment

30 participants

Study Classification

OBSERVATIONAL

Study Start Date

2020-11-04

Study Completion Date

2024-06-30

Brief Summary

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The clinical benefits of endovascular treatment in renal artery stenosis remain controversial. This study uses arterial spin labelling MRI and flat-panel detector parenchymal blood volume imaging to observe the change in renal perfusion after endovascular treatment in renal artery stenosis.

Detailed Description

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Conditions

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Renal Artery Stenosis

Study Design

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Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Study Groups

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Endovascular Group

Patients who had successful endovascular revascularization

No interventions assigned to this group

Eligibility Criteria

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Inclusion Criteria

* patients who provided informed consent
* patients who were diagnosed with RAS by CTA, MRA, or Doppler ultrasonography
* patients who were aged 18 years or older
* patients whose intervened renal arteries were not completely occluded (confirmed by DSA)
* the stenosis percentage exceeding 70%
* patients who had uncontrolled blood pressure or impaired renal function
* paitents whose affected kidney did not have total loss of function

Exclusion Criteria

* were pregnant
* had a history of renal transplantation or renal artery bypass surgery
* were allergic to iodine contrast medium
* had other contraindications of endovascular treatment
* contraindications of MRI examinations
* had technical failure in the endovascular treatment.
Minimum Eligible Age

18 Years

Maximum Eligible Age

80 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Peking Union Medical College Hospital

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Locations

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Peking Union Medical College Hospital

Beijing, , China

Site Status RECRUITING

Countries

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China

Central Contacts

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Bao Liu

Role: CONTACT

010-69152592

Facility Contacts

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Bao Liu, MD

Role: primary

010-69152592

Other Identifiers

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ASL and PBV in RAS

Identifier Type: -

Identifier Source: org_study_id

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