Cognitive Behavioral Therapy(CBT) in Treatment of Methamphetamine Use Disorder

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Clinical Phase

NA

Total Enrollment

50 participants

Study Classification

INTERVENTIONAL

Study Start Date

2023-09-01

Study Completion Date

2025-03-01

Brief Summary

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The efficacy of cognitive behavioral therapy(CBT) in treatment of methamphetamine use disorder

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Detailed Description

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Methamphetamine (MA) use is a serious public health concern in many countries and is second to cannabis as the most widely abused illicit drug in the world.

Over the past few years; there is an alarming increase in crystal methamphetamine (Shabu) abuse in the Egyptian market and The Egyptian government is annoyed from this issue because youth within the age of productivity were targeted.

Regular methamphetamine use can be associated with a range of psychiatric symptoms, particularly psychosis, anxiety, and depression.

No FDA approved pharmacological treatments are available for Meth addiction up till now and despite great advances achieved in understanding the neurobiology of drug addiction, the therapeutic options are severely limited . Consequently, the only available treatment at present is psychosocial intervention.

The effectiveness of CBT for other substance-use disorders (e.g. alcohol-, opioid- and cocaine-use disorders) has been well documented and as such this basic treatment approach has been applied to amphetamine-type stimulant (ATS)-use disorder .

Currently, there is not enough evidence to establish the efficacy of CBT for amphetamine -type stimulant( ATS) -use disorders because of a paucity of high-quality research in this area.

The present study will examine the efficacy of Cognitive behavioral therapy in reducing methamphetamine use in comparison to medical treatment usually taken in methamphetamine use disorder

Conditions

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Methamphetamine Abuse

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

In phase 0:

. These patients will undergo toxicological and psychiatric assessment and will be screened using the inclusion and exclusion criteria.

phase 1:

treatment-as-usual (TAU)- Group offered usual treatment include detoxification, medical care. Clinician-delivered CBT-Group offered 12 weekly, individual sessions of manual-guided CBT (15) delivered by trained clinician .

phase2: a follow-up at 3-month post treatment phase without treatment.

Primary Study Purpose

TREATMENT

Blinding Strategy

NONE

Study Groups

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treatment-as-usual (TAU)

Group Type ACTIVE_COMPARATOR

cognitive behavioral therapy

Intervention Type BEHAVIORAL

12 weekly, individual sessions of manual-guided CBT delivered by trained clinician .

Clinician-delivered CBT with tratment as usual

Group Type ACTIVE_COMPARATOR

cognitive behavioral therapy

Intervention Type BEHAVIORAL

12 weekly, individual sessions of manual-guided CBT delivered by trained clinician .

Interventions

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cognitive behavioral therapy

12 weekly, individual sessions of manual-guided CBT delivered by trained clinician .

Intervention Type BEHAVIORAL

Eligibility Criteria

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Inclusion Criteria

* patients who meet the criteria for methamphetamine use disorder according to Diagnostic and Statistical Manual of Mental Disorders Fifth Edition (DSM 5) (10)
* aged of 15-49 years' old
* more than 9 year of education
* urine drug screening positive for methamphetamine

Exclusion Criteria

* other Axis I disorder of DSM-V criteria such as bipolar disorder, schizophrenia, depression
* Had a legal case pending resulting in inability to commit to 12 weeks of treatment.
* Refusal to participate
* poly drug dependence.

Minimum Eligible Age

15 Years

Maximum Eligible Age

50 Years

Eligible Sex

MALE

Accepts Healthy Volunteers

No