Cognitive Behavioral Therapy for Treatment of Adult Attention Deficit Hyperactivity Disorder

Study Results

Results available

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Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

86 participants

Study Classification

INTERVENTIONAL

Study Start Date

2004-09-30

Study Completion Date

2010-07-31

Brief Summary

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This study will determine the efficacy of cognitive behavioral therapy in treating adults with attention deficit hyperactivity disorder.

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Detailed Description

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Attention deficit hyperactivity disorder (ADHD), previously believed to be a disorder of childhood, affects as many as 5 percent of adults. Adults with ADHD are at high risk for academic and occupational underachievement, relationship difficulties, and reduced quality of life. This study will determine whether cognitive behavioral therapy (CBT) is more effective than ADHD education and relaxation techniques in treating adults with ADHD.

Participants will be randomly assigned to receive 12 to 15 weekly sessions of either CBT or training in which they will learn relaxation techniques and receive detailed information about ADHD. Questionnaires will be used to assess participants' ADHD symptoms at study entry and at study completion.

The study is being conducted at Massachusetts General Hospital in Boston and requires 5 assessment visits and 12 weekly therapy visits. Participants must be able to travel to Boston on a weekly basis in order to participate in the study.

Study hypothesis: CBT is a more efficacious treatment for adult ADHD than education and relaxation techniques.

Conditions

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Attention Deficit Disorder With Hyperactivity

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

NONE

Study Groups

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Cognitive-Behavioral Therapy

Participants will receive cognitive-behavioral therapy following our protocol.

Group Type EXPERIMENTAL

Cognitive behavioral therapy (CBT)

Intervention Type BEHAVIORAL

Participants are provided with education about ADHD and instruction in organizational skills, reducing distractibility, and adaptive thinking.

Relaxation with Educational Support

Applied relaxation plus educational support (RES).

Group Type ACTIVE_COMPARATOR

Relaxation techniques and education about ADHD

Intervention Type OTHER

Participants are provided with education about ADHD, instruction in relaxation techniques, and support in applying relaxation techniques to ADHD symptoms.

Interventions

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Cognitive behavioral therapy (CBT)

Participants are provided with education about ADHD and instruction in organizational skills, reducing distractibility, and adaptive thinking.

Intervention Type BEHAVIORAL

Relaxation techniques and education about ADHD

Participants are provided with education about ADHD, instruction in relaxation techniques, and support in applying relaxation techniques to ADHD symptoms.

Intervention Type OTHER

Other Intervention Names

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Mastering Your Adult ADHD manual (Safren, et al., 2005) Unpublished treatment manual (Sprich, et al., 2003)

Eligibility Criteria

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Inclusion Criteria

* Diagnosis of adult ADHD of at least mild clinical severity (CGI score of 3 or greater)
* Stable on medications for adult ADHD for at least 2 months
* Between 18 and 65 years old
* Be able to give informed consent and comply with study procedures

Exclusion Criteria

* Moderate to severe major depression, clinically significant panic disorder (CGI for depression or panic greater than 4), bipolar disorder, organic mental disorders, psychotic disorders, or pervasive developmental disorders
* Active suicidality (HAM-D suicidality item rated 3 or 4)
* Current substance abuse or dependence
* IQ less than 90
* Suicide risk
* Prior participation in cognitive behavioral therapy for ADHD

Minimum Eligible Age

18 Years

Maximum Eligible Age

65 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No