Evaluating the Effectiveness of Ondansetron Versus Dexamethasone Versus Placebo for the Control of Intraoperative Nausea and Vomiting in Patients Undergoing Lower-segment Caesarean Section Under Spinal Anesthesia
NCT ID: NCT05583214
Last Updated: 2022-10-18
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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UNKNOWN
PHASE4
90 participants
INTERVENTIONAL
2022-10-31
2023-01-31
Brief Summary
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Which drug is the best at reducing the incidence of intraoperative nausea and vomiting.
Which drug is the best at reducing intraoperative pain.
Participants will be randomly divided into three groups, each will be given a different drug labelled A, B, or C.
A rating scale will be used to evaluate the severity of intraoperative nausea and pain. Episodes of vomiting will be recorded.
Data collected from the three groups will be analyzed using SPSS software.
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Detailed Description
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Conditions
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Study Design
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RANDOMIZED
PARALLEL
PREVENTION
TRIPLE
Study Groups
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Ondansetron
Patients given Ondansetron (8mg)
Ondansetron 8mg
8mg of Ondansetron IV stat will be given to the group after induction of spinal anesthesia
Dexamethasone
Patients given Dexamethasone (8mg)
Dexamethasone 8mg
8mg of Dexamethasone IV stat will be given to the group after induction of spinal anesthesia
Placebo
Normal saline
Normal saline will be given IV stat to the group after induction of spinal anesthesia
Interventions
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Ondansetron 8mg
8mg of Ondansetron IV stat will be given to the group after induction of spinal anesthesia
Dexamethasone 8mg
8mg of Dexamethasone IV stat will be given to the group after induction of spinal anesthesia
Normal saline
Normal saline will be given IV stat to the group after induction of spinal anesthesia
Eligibility Criteria
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Inclusion Criteria
* Given informed consent
* No contraindication to spinal anesthesia
* ASA I or II
Exclusion Criteria
* Non-consenting
* Contraindication to spinal anesthesia
* ASA III or IV
20 Years
35 Years
FEMALE
Yes
Sponsors
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Muhammad Mubariz
OTHER
Responsible Party
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Muhammad Mubariz
House Officer
Principal Investigators
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Muhammad Mubariz, MBBS
Role: PRINCIPAL_INVESTIGATOR
House Officer
Locations
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Akhtar Saeed Trust Hospital
Lahore, Punjab Province, Pakistan
Countries
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Central Contacts
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Facility Contacts
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Other Identifiers
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UMO708991
Identifier Type: -
Identifier Source: org_study_id
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