Prevalence and Genetic Alternation of Autoimmune Polyglandular Syndrome Type II in Taiwan

NCT ID: NCT05578105

Last Updated: 2022-10-13

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

RECRUITING

Total Enrollment

650 participants

Study Classification

OBSERVATIONAL

Study Start Date

2022-01-01

Study Completion Date

2026-12-31

Brief Summary

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Autoimmune polyendocrine syndrome (APS) is an autoimmune disease involving at least two endocrine organ. It is classified into type I and type II diseases. Among them, APS type II is more common. It is diagnosed when two of the three following diseases are diagnosed in the same patient, including type 1 diabetes mellitus, autoimmune thyroid disease, and primary adrenal insufficiency. In this study, we will observe the epidemiology, clinical characteristics, and genetic variants of APS II in Taiwan.

Detailed Description

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Conditions

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Autoimmune Polyendocrine Syndrome Type II

Study Design

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Observational Model Type

CASE_ONLY

Study Time Perspective

RETROSPECTIVE

Study Groups

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Autoimmune polyendocrine syndrome type II

patients with autoimmune polyendocrine syndrome type II

no intervention

Intervention Type OTHER

No intervention, only observation

Interventions

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no intervention

No intervention, only observation

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* Patients visited NTUH during 2006-2021, and had at least two of the three diseases: type 1 DM, primary adrenal insufficiency, and autoimmune thyroid disease.

Exclusion Criteria

* Patients aged less than 20 years old
Minimum Eligible Age

20 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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National Taiwan University Hospital

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Shyang-Rong Shih, MD, PhD

Role: STUDY_DIRECTOR

National Taiwan University Hospital

Locations

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National Taiwan University Hospital

Taipei, , Taiwan

Site Status RECRUITING

Countries

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Taiwan

Central Contacts

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Shyang-Rong Shih, MD, PhD

Role: CONTACT

+886-972653337

Facility Contacts

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Shyang-Rong Shih, MD. PhD

Role: primary

+886-972653337

Other Identifiers

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202112250RINC

Identifier Type: -

Identifier Source: org_study_id

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