Hemodynamic Stability in Septic Shock Patients Undergoing Continuous Renal Replacement Therapy With oXiris Membrane
NCT ID: NCT05575024
Last Updated: 2025-05-15
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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RECRUITING
98 participants
OBSERVATIONAL
2024-01-01
2026-12-31
Brief Summary
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Detailed Description
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The patient outcomes include cardiovascular, respiratory, renal, and overall survivals, but this information of oXiris are insufficient. Although cytokine and endotoxin removal rates are great in oXiris, the beneficial effects on the hard outcomes are needed to use oXiris in real clinical practice.
The inflammatory and cardiovascular systems have intensive crosstalk, and thus if there are remission in inflammatory process, the patients can have hemodynamic stability. Regarding this, the investigators would like to compare the hemodynamic stability between oXiris and other standard membrane such as polysulfone, using our new real-time monitoring registry.
Conditions
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Study Design
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CASE_CONTROL
PROSPECTIVE
Study Groups
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Septic AKI
Patients with septic acute kidney injury requiring continuous renal replacement therapy
oXiris membrane
Perform continuous renal replacement therapy with oXiris membrane
Polysulfone membrane
Perform continuous renal replacement therapy with polysulfone membrane
Interventions
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oXiris membrane
Perform continuous renal replacement therapy with oXiris membrane
Polysulfone membrane
Perform continuous renal replacement therapy with polysulfone membrane
Eligibility Criteria
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Inclusion Criteria
* Sepsis related acute kidney injury requiring continuous renal replacement therapy
Exclusion Criteria
18 Years
ALL
No
Sponsors
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Seoul National University Hospital
OTHER
Responsible Party
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Seung Seok Han, MD
Associate Professor
Principal Investigators
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Seung Seok Han, M.D.
Role: PRINCIPAL_INVESTIGATOR
Seoul National University Hospital
Locations
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Seoul National University Hospital
Seoul, , South Korea
Countries
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Central Contacts
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Facility Contacts
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Other Identifiers
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2021-4067
Identifier Type: -
Identifier Source: org_study_id
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