Effects of Different Doses of Vitamin D on Cancer-related Cognitive Impairment in Patients With Gastrointestinal Tumors
NCT ID: NCT05552729
Last Updated: 2022-09-23
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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UNKNOWN
PHASE1/PHASE2
114 participants
INTERVENTIONAL
2022-09-22
2022-12-30
Brief Summary
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Detailed Description
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Conditions
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Study Design
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RANDOMIZED
PARALLEL
TREATMENT
SINGLE
Study Groups
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High dose group
A 2000IU vitamin D3 supplement was started the next day after surgery.
Vitamin D
The patients were given vitamin D supplementation 48 hours after surgery, and the two groups were given different doses of vitamin D supplementation until the postoperative discharge criteria were met. To scientifically evaluate the application effect of early postoperative vitamin D intervention in the improvement of perioperative cognitive function in patients with gastrointestinal tumors.
Low dose group
A 400IU vitamin D3 supplement was started the next day after surgery.
Vitamin D
The patients were given vitamin D supplementation 48 hours after surgery, and the two groups were given different doses of vitamin D supplementation until the postoperative discharge criteria were met. To scientifically evaluate the application effect of early postoperative vitamin D intervention in the improvement of perioperative cognitive function in patients with gastrointestinal tumors.
The control group.
No vitamin D3 supplement was started the next day after surgery.
No interventions assigned to this group
Interventions
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Vitamin D
The patients were given vitamin D supplementation 48 hours after surgery, and the two groups were given different doses of vitamin D supplementation until the postoperative discharge criteria were met. To scientifically evaluate the application effect of early postoperative vitamin D intervention in the improvement of perioperative cognitive function in patients with gastrointestinal tumors.
Other Intervention Names
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Eligibility Criteria
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Inclusion Criteria
* Elective surgery
* Education level in primary school or above
* Be able to fill in the questionnaire alone or under the guidance of the researcher
* Informed consent and voluntary participation in this study
Exclusion Criteria
* Patients with life-threatening acute and chronic diseases
* Patients with eye or ear diseases leading to rapid loss of hearing or vision without AIDS
* Patients who have taken drugs related to improving cognitive function or drugs for psychiatric disorders
* Patients who cannot take care of themselves or are physically disabled and unable to perform neurological function tests
* Intraoperative hypoxemia (blood oxygen saturation \< 94％) more than 10 minutes
* Patients who quit or died due to non-cooperation or emergency
18 Years
ALL
No
Sponsors
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Subei People's Hospital of Jiangsu Province
OTHER
Yangzhou University
OTHER
Responsible Party
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Wang Daorong
Professor
Principal Investigators
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Daorong Wang, Professor
Role: STUDY_DIRECTOR
Yangzhou University
Locations
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Daorong Wang
Yangzhou, Jiangsu, China
Countries
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Central Contacts
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Other Identifiers
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Yangzhou University
Identifier Type: -
Identifier Source: org_study_id
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