Multi-omics Analysis of Chronic Kidney Disease

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Total Enrollment

150 participants

Study Classification

OBSERVATIONAL

Study Start Date

2022-01-01

Study Completion Date

2024-12-31

Brief Summary

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Chronic kidney disease (CKD) is a progressive disease with hidden epidemics and one of the most significant contributing factors to end-stage renal disease (ESRD), cardiovascular comorbidities, cachexia and anemia, which accounts for a nearly 1.2 million populations died per year.

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Detailed Description

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Conditions

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Potential Mechanisms Underlying the Microbiota-Gut-Kidney Axis in CKD

Study Design

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Observational Model Type

COHORT

Study Time Perspective

CROSS_SECTIONAL

Study Groups

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healthy controls

renal function

Intervention Type BEHAVIORAL

levels of eGFR

mild CKD

renal function

Intervention Type BEHAVIORAL

levels of eGFR

Moderate CKD

renal function

Intervention Type BEHAVIORAL

levels of eGFR

ESRD

renal function

Intervention Type BEHAVIORAL

levels of eGFR

Interventions

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renal function

levels of eGFR

Intervention Type BEHAVIORAL

Eligibility Criteria

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Inclusion Criteria

Age-matched and gender-matched HC with normal renal and liver function and not taking any medications were enrolled

Exclusion Criteria

1. Age\<18 years.
2. Individuals with hypertension, diabetes, obesity, metabolic syndrome or pregnancy.
3. Individuals who received gastrointestinal operation, antibiotics or probiotic products within one month.

Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes