Uremic Toxins and Outcomes in Chronic Kidney Disease

NCT ID: NCT03711617

Last Updated: 2024-12-03

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

RECRUITING

Total Enrollment

500 participants

Study Classification

OBSERVATIONAL

Study Start Date

2018-05-01

Study Completion Date

2024-12-31

Brief Summary

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The aim of this cohort study is:

To investigate the etiology and epidemiology of comorbidities in CKD; To find out risk factors associated with the mortality of CKD; To find out uremic toxins which are related to the mortality and comorbidities of CKD; To focuse on the association between uremic toxins and inflammation, oxidative stress and nutritional status in CKD.

Detailed Description

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To investigate the etiology and epidemiology of comorbidities in CKD; To find out risk factors associated with the mortality of CKD; To find out uremic toxins which are related to the mortality and comorbidities of CKD; To focuse on the association between uremic toxins and inflammation, oxidative stress and nutritional status in CKD.

Conditions

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Chronic Kidney Diseases

Study Design

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Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Study Groups

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CKD-ND

patients with non-dialysis CKD

No interventions assigned to this group

CKD-MHD

patients with maintenance hemodialysis

No interventions assigned to this group

Eligibility Criteria

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Inclusion Criteria

* age ≥18 years old;
* clinically diagnosed with chronic kidney disease, according K/DOQI criteria.

Exclusion Criteria

* acute kidney injury
* history of kidney injury \<3 months
* malignancy
* pregnancy
* incomplete clinical data
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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Shanghai Ninth People's Hospital Affiliated to Shanghai Jiao Tong University

OTHER

Sponsor Role lead

Responsible Party

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Ding Feng

Director of Devision of Nephrology

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Feng Ding, PhD

Role: STUDY_CHAIR

Division of Nephrology, Shanghai Ninth People's Hospital, School of Medicine, Shanghai Jiaotong University

Locations

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Shanghai Ninth People's Hospital

Shanghai, Shanghai Municipality, China

Site Status RECRUITING

Countries

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China

Central Contacts

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Feng Ding, PhD

Role: CONTACT

86-21-53315165

Wenji Wang, MD

Role: CONTACT

86-21-53315165

Facility Contacts

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Feng Ding, PhD

Role: primary

86-21-53315165

Other Identifiers

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CKD-toxins

Identifier Type: -

Identifier Source: org_study_id