Aetiology of Asymmetrical Hearing Loss: A Retro-spective Study Thesis Submitted for Partial Fulfillment of Master Degree in Audio-Vestibular Medicine

NCT ID: NCT05543135

Last Updated: 2022-09-16

Basic Information

• Recruitment Status: UNKNOWN
• Total Enrollment: 50 participants
• Study Classification: OBSERVATIONAL
• Study Start Date: 2022-09-20
• Study Completion Date: 2023-09-30

Brief Summary

Hearing loss maybe: -Symmetrical: in which the severity and pattern of hearing loss are the same in each ear. Or -Asymmetrical: is defined as binaural difference in bone conduction thresholds of >10 dB at two consecutive frequencies or >20 dB at one frequency (0.25-8.0 kHz), Poorer speech perception will often accompany poorer hearing and may be the reason for the patient's presentation .Unilateral or asymmetrical sensorineural hearing loss is important to discern, as it is an important risk factor for auditory nerve tumors (i.e. vestibular schwannoma) which is a life threatening condition, and in such cases further investigation is required (i.e. MRI scan) unless there is a known reason for the asymmetry, Several reports have recommended that further evaluation, especially expensive imaging studies, be conducted to rule out acoustic tumors when AHL is present

Conditions

Asymmetrical Hearing Loss

Study Design

• Observational Model Type: CASE_ONLY
• Study Time Perspective: RETROSPECTIVE

Study Groups

cases

patients with asymmetrical hearing loss

basic audiological evaluation

Intervention Type: DIAGNOSTIC_TEST

pure tone audiometry\&immitancemetry

Interventions

basic audiological evaluation

pure tone audiometry\&immitancemetry

Intervention Type: DIAGNOSTIC_TEST

Other Intervention Names

CT&MRI

Eligibility Criteria

Inclusion Criteria

• Age: 6 years old and more.
• Sex: male and female.

Exclusion Criteria

• Age: less than 6 years old.
• Patients with symmetrical hearing loss.

• Minimum Eligible Age: 6 Years
• Eligible Sex: ALL
• Accepts Healthy Volunteers: No

Sponsors

Sohag University

OTHER

Sponsor Role: lead

Responsible Party

Inas Mahmoud Mahrous

resident doctor at audiovestibular unit Qena general hospital

Responsibility Role: PRINCIPAL_INVESTIGATOR

Locations

Sohag University Hospital

Sohag, , Egypt

Countries

Egypt

Central Contacts

Enas M Mahrous, resident doctor

Role: CONTACT

inas_mahmoud_post@med.sohag.edu.eg

01096769904

Mohamed A Abdelrahman, professor

Role: CONTACT

Facility Contacts

Magdy M Amin, professor

Role: primary

References

Dunn CC, Tyler RS, Oakley S, Gantz BJ, Noble W. Comparison of speech recognition and localization performance in bilateral and unilateral cochlear implant users matched on duration of deafness and age at implantation. Ear Hear. 2008 Jun;29(3):352-9. doi: 10.1097/AUD.0b013e318167b870.

Reference Type: BACKGROUND

PMID: 18453885 (View on PubMed)

Margolis RH, Saly GL. Asymmetric hearing loss: definition, validation, and prevalence. Otol Neurotol. 2008 Jun;29(4):422-31. doi: 10.1097/MAO.0b013e31816c7c09.

Reference Type: BACKGROUND

PMID: 18418281 (View on PubMed)

Peng AW, Salles FT, Pan B, Ricci AJ. Integrating the biophysical and molecular mechanisms of auditory hair cell mechanotransduction. Nat Commun. 2011 Nov 1;2:523. doi: 10.1038/ncomms1533.

Reference Type: BACKGROUND

PMID: 22045002 (View on PubMed)

Plack CJ, Barker D, Hall DA. Pitch coding and pitch processing in the human brain. Hear Res. 2014 Jan;307:53-64. doi: 10.1016/j.heares.2013.07.020. Epub 2013 Aug 11.

Reference Type: BACKGROUND

PMID: 23938209 (View on PubMed)

Other Identifiers

Soh-Med-22-07-09

Identifier Type: -

Identifier Source: org_study_id