Edaravone in the Treatment of Optic Neuritis

NCT ID: NCT05540262

Last Updated: 2025-02-27

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

RECRUITING

Clinical Phase

NA

Total Enrollment

50 participants

Study Classification

INTERVENTIONAL

Study Start Date

2022-01-15

Study Completion Date

2025-12-31

Brief Summary

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Edaravone has demonstrated a beneficial effect in promoting remyelination and protecting axons in animals with NMOSD. The researchers posit that edaravone may enhance visual outcomes in patients with aquaporin-4 antibody-positive optic neuritis.

Detailed Description

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Conditions

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Optic Neuritis

Study Design

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Allocation Method

NA

Intervention Model

SINGLE_GROUP

Primary Study Purpose

TREATMENT

Blinding Strategy

NONE

Study Groups

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Edaravone

Group Type EXPERIMENTAL

Edaravone

Intervention Type DRUG

Edaravone injection 30mg three times a day

Interventions

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Edaravone

Edaravone injection 30mg three times a day

Intervention Type DRUG

Eligibility Criteria

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Inclusion Criteria

1. Chinese patients aged ≥18 with anti-aquaporin-4 antibody-positive optic neuritis
2. Patients with a first episode of optic neuritis in either eye
3. First symptoms of optic neuritis ≤30 days prior to the first administration of edaravone

Exclusion Criteria

1. Myopia over 6 diopters
2. Refractive media opacity affecting assessment of retinal layers and/or visual acuity
Minimum Eligible Age

18 Years

Maximum Eligible Age

70 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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First Affiliated Hospital of Guangxi Medical University

OTHER

Sponsor Role lead

Responsible Party

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Yi Du

Dr.

Responsibility Role PRINCIPAL_INVESTIGATOR

Locations

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Yi Du

Nanning, , China

Site Status RECRUITING

Countries

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China

Facility Contacts

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Yi Du, MD

Role: primary

+86 771 5356507

Other Identifiers

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GXEDAON1.0

Identifier Type: -

Identifier Source: org_study_id

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