Nutritional Status and ASD Severity of Autistic Spectrum Disorder Children in Addis Ababa, Ethiopia; Case Control Study

NCT ID: NCT05515913

Last Updated: 2022-08-25

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

52 participants

Study Classification

OBSERVATIONAL

Study Start Date

2021-08-14

Study Completion Date

2022-02-08

Brief Summary

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The study conducts a case control analysis of the nutritional status and intake of autistic spectrum disorder diagnosed children as compared to typically developing children in Addis Ababa, Ethiopia. It included analysis of anthropometric measurements, three days food diary food intake, urinary iodine analysis, childhood autism rating scale diagnosis, food frequency and eating behavior questioner and proximate analysis of one day major meals of selected subjects.

Detailed Description

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Sample population was Addis Ababa city in which subjects were selected from one of the two autism centers in the country. Random sampling method was applied to select subject from the total enrolled children in the center using Ryan 2013 sample size calculation formula.

Subjects already diagnose with autistic spectrum disorder that didn't have any other chronic disease that affect diet and nutrition were included in the study. Subjects were selected randomly from each grade level in the center. They were registered and taken for data collection. Sample and Data was collected with the help of each child's center caregiver and parent. Childhood autism rating scale diagnosis, eating behavior analysis were analyzed for the ASD and anthropometric indices Z scores, urine iodine concentration, three days food diary analysis, major meals proximate analysis, food frequency and dietary diversity was assessed and compared to typically developing children in Addis Ababa.

Data entry and analysis was conducted using Emergency Nutrition Assessment software, Microsoft excel and Statistical Package for the Social Sciences software.

Conditions

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Autistic Spectrum Disorder

Study Design

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Observational Model Type

CASE_CONTROL

Study Time Perspective

PROSPECTIVE

Study Groups

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ASD ( autistic spectrum disorder)

Children already diagnosed with autistic spectrum disorder

Nutritional status

Intervention Type OTHER

Nutritional status of children as analyzed by anthropometric indices was under study

Eating behavior

Intervention Type BEHAVIORAL

The eating behavior of ASD children as analyzed by frequency of refusal of new food, sensitivity to food, food allergy and gastrointestinal systems was under study

Urine iodine concentration

Intervention Type OTHER

the 24 urine iodine concentration of all subjects was under study

Nutrient intake

Intervention Type OTHER

The nutrient intake as analyzed by three days food diary and major meal proximate analysis of subjects was under study

Dietary assessment

Intervention Type OTHER

The food frequency and dietary diversity of all subjects as analyzed by food frequency questioner, dietary diversity score and food variety score was under study

Childhood autism rating scale

Intervention Type OTHER

The autistic severity of ASD diagnosed children was under study as analyzed by childhood autism rating scale diagnosis

TDC (typically developing children)

Children within the typically development

Nutritional status

Intervention Type OTHER

Nutritional status of children as analyzed by anthropometric indices was under study

Urine iodine concentration

Intervention Type OTHER

the 24 urine iodine concentration of all subjects was under study

Nutrient intake

Intervention Type OTHER

The nutrient intake as analyzed by three days food diary and major meal proximate analysis of subjects was under study

Dietary assessment

Intervention Type OTHER

The food frequency and dietary diversity of all subjects as analyzed by food frequency questioner, dietary diversity score and food variety score was under study

Interventions

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Nutritional status

Nutritional status of children as analyzed by anthropometric indices was under study

Intervention Type OTHER

Eating behavior

The eating behavior of ASD children as analyzed by frequency of refusal of new food, sensitivity to food, food allergy and gastrointestinal systems was under study

Intervention Type BEHAVIORAL

Urine iodine concentration

the 24 urine iodine concentration of all subjects was under study

Intervention Type OTHER

Nutrient intake

The nutrient intake as analyzed by three days food diary and major meal proximate analysis of subjects was under study

Intervention Type OTHER

Dietary assessment

The food frequency and dietary diversity of all subjects as analyzed by food frequency questioner, dietary diversity score and food variety score was under study

Intervention Type OTHER

Childhood autism rating scale

The autistic severity of ASD diagnosed children was under study as analyzed by childhood autism rating scale diagnosis

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* Children already diagnosed with ASD
* school aged children (4-18 years old)

Exclusion Criteria

* children with chronic illnesses ( such as cancer..)
* children taking heavy medications that may affect diet and nutrition
Minimum Eligible Age

4 Years

Maximum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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Addis Ababa University

OTHER

Sponsor Role lead

Responsible Party

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Feven yirgu Tamire

Principal Investigator

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Feven Yirgu Tamire

Role: PRINCIPAL_INVESTIGATOR

Addis Ababa Science and Technology University

Locations

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Addis Ababa Science and Technology University

Addis Ababa, , Ethiopia

Site Status

Countries

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Ethiopia

Provided Documents

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Document Type: Study Protocol and Statistical Analysis Plan

View Document

Document Type: Informed Consent Form

View Document

Other Identifiers

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AASTUASD

Identifier Type: -

Identifier Source: org_study_id

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