Relationship Between Effect Duration of Rocuronium and Body Composition Analysis Data.

NCT ID: NCT05515835

Last Updated: 2023-01-04

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Total Enrollment

88 participants

Study Classification

OBSERVATIONAL

Study Start Date

2022-09-05

Study Completion Date

2023-03-31

Brief Summary

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The induction dose of rocuronium is typically decided based on the patient's body weight, but the effect duration of rocuronium is variable. Some studies suggest that body composition analysis data, such as skeletal muscle mass or total body water, may correlate better with the duration time of rocuronium. Therefore, we plan to analyse body composition in patients undergoing total intravenous general anesthesia, give the patients a fixed dose (50mg) of rocuronium, and check the correlation between duration time of rocuronium and body composition analysis data.

Detailed Description

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Conditions

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Rocuronium Body Composition

Study Design

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Observational Model Type

OTHER

Study Time Perspective

PROSPECTIVE

Study Groups

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rocuronium

The patient will be given 50mg of rocuronium intravenously for induction.

body composition analysis

Intervention Type DEVICE

Patients will undergo body composition analysis using bioelectical impedance method before anesthesia.

Interventions

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body composition analysis

Patients will undergo body composition analysis using bioelectical impedance method before anesthesia.

Intervention Type DEVICE

Eligibility Criteria

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Inclusion Criteria

* Adult patients with ASA class I-II undergoing total intravenous general anesthesia

Exclusion Criteria

* too overweight (over 111.11kg, which corresponds to less than 0.45mg/kg of induction dose of rocuronium)
* too underweight (under 41.67kg, which corresponds to more than 1.2mg/kg of induction dose of rocuronium)
* pregnancy
* prediagnosed muscle or nerve related disease
* unsuitable for body composition analysis using bioelectrical impedance method
* unsuitable for neuromuscular block monitoring
Minimum Eligible Age

19 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Samsung Medical Center

OTHER

Sponsor Role lead

Responsible Party

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Jong Hwan Lee

Prof.

Responsibility Role PRINCIPAL_INVESTIGATOR

Locations

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Samsung Medical Center, Sungkyunkwan University, School of Medicine

Seoul, , South Korea

Site Status

Countries

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South Korea

Other Identifiers

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SMC 2022-07-160

Identifier Type: -

Identifier Source: org_study_id

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