Human Irisin Concentration in Sarcopenia

NCT ID: NCT01874912

Last Updated: 2013-06-11

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

406 participants

Study Classification

OBSERVATIONAL

Study Start Date

2009-11-30

Study Completion Date

2011-04-30

Brief Summary

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Irisin has been identified as a novel myokine that drives brown-fat-like conversion of white adipose tissue. In this cross-sectional study, the researches investigated whether serum irisin levels are decreased in patients with sarcopenia compared with control subjects with normal muscle mass, and assessed the association between serum irisin levels and various metabolic parameters.

Detailed Description

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Conditions

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Sarcopenia

Study Design

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Observational Model Type

COHORT

Study Time Perspective

CROSS_SECTIONAL

Eligibility Criteria

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Inclusion Criteria

* 20\<age\<80
* apparently healthy subjects

Exclusion Criteria

* a history of cardiovascular disease
* diabetes
* stage 2 hypertension
* malignancy
* severe renal or hepatic disease
Minimum Eligible Age

20 Years

Maximum Eligible Age

80 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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Korea University

OTHER

Sponsor Role lead

Responsible Party

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K. M. Choi

Professor

Responsibility Role PRINCIPAL_INVESTIGATOR

Locations

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Korea University Guro Hospital

Seoul, , South Korea

Site Status

Countries

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South Korea

References

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Choi HY, Kim S, Park JW, Lee NS, Hwang SY, Huh JY, Hong HC, Yoo HJ, Baik SH, Youn BS, Mantzoros CS, Choi KM. Implication of circulating irisin levels with brown adipose tissue and sarcopenia in humans. J Clin Endocrinol Metab. 2014 Aug;99(8):2778-85. doi: 10.1210/jc.2014-1195. Epub 2014 Apr 29.

Reference Type DERIVED
PMID: 24780049 (View on PubMed)

Other Identifiers

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SO(IRISIN)

Identifier Type: -

Identifier Source: org_study_id

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