Exploring Central Sensitization in Pregnant Women

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

Get a concise snapshot of the trial, including recruitment status, study phase, enrollment targets, and key timeline milestones.

Recruitment Status

RECRUITING

Total Enrollment

144 participants

Study Classification

OBSERVATIONAL

Study Start Date

2023-08-15

Study Completion Date

2025-12-31

Brief Summary

Review the sponsor-provided synopsis that highlights what the study is about and why it is being conducted.

Pelvic Girdle Pain (PGP) is reported by 50% of pregnant women and up to 11 years after pregnancy, 10% of women have persistent and per definition chronic PGP. Central (nervous system) sensitization that elicits pain hypersensitivity, may be one explanation.

The overall aim of this study is to explore features of central sensitization in pregnant women and its predictive ability on physical activity, functioning and health in women with PGP. Measurements of central sensitization will be done on two study groups, pregnant women with PGP and healthy controls. To identify women at risk to develop chronic pain in relation to a common pain experience ie PGP in pregnancy, may help us understand if central sensitization early in life explains why women develop chronic pain.

Related Clinical Trials

Explore similar clinical trials based on study characteristics and research focus.

The Role of Proprioceptive Deficits, Psychosocial Factors and Inflammation in Pregnancy-related Pelvic Girdle Pain

NCT04226716

Pelvic Girdle Pain Low Back Pain

RECRUITING NA

Treatment of Low Back Pain in Pregnant Women : Uses of Drugs and Other Therapies

NCT05072002

Low Back Pain Pregnancy Related

COMPLETED

WOMENinMOTION An Intervention Model for Pelvic Girdle Pain

NCT07158957

Pelvic Girdle Pain Physical Activity

RECRUITING NA

Screening for Pregnancy Related Pelvic Girdle Pain

NCT05382845

Pelvic Girdle Pain

RECRUITING NA

Pelvic Girdle Pain in a Pregnant Population in Western Norway.

NCT01098136

Pelvic Girdle Pain

COMPLETED NA

Detailed Description

Dive into the extended narrative that explains the scientific background, objectives, and procedures in greater depth.

Pelvic Girdle Pain (PGP) is reported by 50% (60000) of pregnant women yearly in Sweden. PGP is expected to disappear after delivery. However up to 11 years after pregnancy, 10% of women have persistent and per definition chronic PGP with large impact on their physical activity, functioning,and health. Central (nervous system) sensitization, defined as an amplification of neural signaling within the central nervous system that elicits pain hypersensitivity, may be one explanation why 10% of women develop postpartum chronic PGP and related physical inactivity.

The overall aim of this study is to explore features of central sensitization in pregnant women and its predictive ability on physical activity, functioning and health in women with PGP. Two study groups, pregnant women with PGP and healthy controls (including non-native Swedish) will be included through maternity care units and a blog. Measurements of primary outcome central sensitization will be done. To identify women at risk to develop chronic pain in relation to a common pain experience ie PGP in pregnancy, may help us understand if central sensitization early in life explains why women develop chronic pain.

Conditions

See the medical conditions and disease areas that this research is targeting or investigating.

Pelvic Girdle Pain Chronic Pain

Study Design

Understand how the trial is structured, including allocation methods, masking strategies, primary purpose, and other design elements.

Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Eligibility Criteria

Check the participation requirements, including inclusion and exclusion rules, age limits, and whether healthy volunteers are accepted.

Inclusion Criteria

* pregnant (first time pregnant or previous experience of pregnancy)
* 18 years of age or older
* have a single foetus pregnancy
* be in gestational weeks 20-30
* able to read and understand Swedish or English

Exclusion Criteria

* no history of a fracture or malignant disease in the back, pelvis, pelvic floor or hips
* no systemic disease of the musculoskeletal or the nervous system
* no diseases such as gestational diabetes or diabetes type 1 and 2, hypertension
* no obstetric complications
* no contradiction for tests.

Minimum Eligible Age

18 Years

Eligible Sex

FEMALE

Accepts Healthy Volunteers

Yes