Foley Balloon Study for Cervical Ripening - Cost Comparison Between Outpatient and Inpatient Cervical Ripening

NCT ID: NCT05506631

Last Updated: 2025-05-31

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

Get a concise snapshot of the trial, including recruitment status, study phase, enrollment targets, and key timeline milestones.

Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

140 participants

Study Classification

INTERVENTIONAL

Study Start Date

2021-11-01

Study Completion Date

2024-10-30

Brief Summary

Review the sponsor-provided synopsis that highlights what the study is about and why it is being conducted.

The objective of this study is to determine the impact of outpatient cervical ripening with transcervical balloon placement for induction of labor at term on the length and cost of inpatient hospitalization when compared to inpatient cervical ripening.

Detailed Description

Dive into the extended narrative that explains the scientific background, objectives, and procedures in greater depth.

The objective of the study is to determine the impact of outpatient cervical ripening with transcervical balloon placement for induction of labor at term on the length and cost of inpatient hospitalization when compared to inpatient cervical ripening.

Specific Aims

In conducting this study, the investigators will accomplish the following specific aim:

To compare the length of inpatient care for women undergoing cervical ripening with a transcervical Foley placed in the outpatient vs. inpatient setting prior to induction of labor.

* Primary outcomes of interest
* The length of time (measured in minutes) spent on the inpatient unit (L\&D) from admission for cervical ripening and/or labor induction until delivery.

Outpatient arm:

Time for the participants in the outpatient group will be measured from the time the participant is admitted to the hospital for induction of labor until she delivers.

Inpatient arm:

Time for the participant in the inpatient group will be measured from the time the participant is admitted to the hospital for cervical ripening with balloon placement and induction until she delivers.

Time from admission to L\&D until delivery = total INPATIENT until delivery (hours)

• Cost Analysis

Cost/charges will be calculated for the time spent in the outpatient and inpatient unit for both randomization groups.

Cost will be based on information obtained from Enterprise Analytics charges for the time each participant spends in outpatient care, inpatient care, hospitalized from admission to the L\&D unit to delivery.

The investigators will report on the delta/difference in average costs of outpatient and inpatient care between the outpatient and inpatient arms of the study.

Information will be obtained from the finance department at LVHN.

* Secondary outcomes of interest to be compared by randomization groups include:
* maternal outcomes
* mode of delivery, chorioamnionitis, endometritis, placental abruption, urinary tract infection, preeclampsia, wound infection, venous thromboembolism, maternal treatment with postpartum antibiotics
* neonatal outcomes
* neonatal birthweight, Apgar scores, admission to the neonatal intensive care unit (ICU), neonatal ICU length of stay, neonatal hypoglycemia, neonatal sepsis, neonatal seizures, meconium aspiration, intubation for respiratory support, neonatal length of stay (total), umbilical cord gas pH, neonatal death or stillbirth
* dosing of narcotic medications before regional anesthesia
* total oxytocin infusion dosing
* total length of stay for mothers and neonates

Conditions

See the medical conditions and disease areas that this research is targeting or investigating.

Pregnancy Outcome

Study Design

Understand how the trial is structured, including allocation methods, masking strategies, primary purpose, and other design elements.

Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Randomized controlled trial
Primary Study Purpose

TREATMENT

Blinding Strategy

NONE

Study Groups

Review each arm or cohort in the study, along with the interventions and objectives associated with them.

Outpatient cervical ripening

Placement of transcervical Foley balloon for cervical ripening in outpatient setting

Group Type EXPERIMENTAL

Outpatient Foley balloon placement

Intervention Type PROCEDURE

Cervical ripening with balloon placement in the outpatient setting

Inpatient cervical ripening

Placement of transcervical Foley balloon for cervical ripening in inpatient setting

Group Type ACTIVE_COMPARATOR

Inpatient Foley Balloon placement

Intervention Type PROCEDURE

Cervical ripening with balloon placement in the inpatient setting

Interventions

Learn about the drugs, procedures, or behavioral strategies being tested and how they are applied within this trial.

Outpatient Foley balloon placement

Cervical ripening with balloon placement in the outpatient setting

Intervention Type PROCEDURE

Inpatient Foley Balloon placement

Cervical ripening with balloon placement in the inpatient setting

Intervention Type PROCEDURE

Eligibility Criteria

Check the participation requirements, including inclusion and exclusion rules, age limits, and whether healthy volunteers are accepted.

Inclusion Criteria

* Pregnant women at ≥39 weeks gestation by reliable dating criteria as determined by the American College of Obstetricians and Gynecologists
* Scheduled induction of labor with indication and timing supported by Lehigh Valley Health Network -Labor and Delivery Units (Cedar Crest \& Muhlenberg)
* Singleton gestation
* Cephalic presentation
* Amniotic fluid index normal
* Formal prenatal ultrasound during the pregnancy documenting the absence of placenta previa
* Bishop score \<6 and cervical dilation \<3cm at the time of decision to induce labor
* The woman is able to give appropriate consent and has undergone an informed consent process.
* Maternal age ≥ 18 years old at the time of consent
* English speaking

Exclusion Criteria

* Undergoing outpatient antenatal testing for any medical or obstetric condition
* Need for inpatient observation or continuous fetal monitoring during their cervical ripening
* New diagnosis requiring immediate hospitalization for monitoring (such as new onset hypertensive disease of pregnancy)
* Vaginal bleeding
* Active labor
* Premature rupture of membranes
* Uterine tachysystole (\>5 contractions in 10 minutes)
* Non-reassuring fetal heart tracing before Foley placement
* Intrauterine fetal demise diagnosed after enrollment and before placement of balloon
* Contraindication to vaginal delivery, relative or absolute (i.e. transfundal uterine surgery)
* Abnormal placentation including a low lying placenta
* Prior cesarean delivery
* Known fetal major anomaly
* Human immunodeficiency virus, Hepatitis C, or active herpes infection
* Maternal cardiopulmonary disease requiring cardiac monitoring during labor
* Pregestational diabetes or GDMA2
* Rh isoimmunization
* Non-English speaking
* BMI \> 40
* Distance from the hospital over 60 minutes by car, unreliable communication via telephone, or unreliable transportation
Minimum Eligible Age

18 Years

Maximum Eligible Age

39 Years

Eligible Sex

FEMALE

Accepts Healthy Volunteers

Yes

Sponsors

Meet the organizations funding or collaborating on the study and learn about their roles.

Lehigh Valley Hospital

OTHER

Sponsor Role lead

Responsible Party

Identify the individual or organization who holds primary responsibility for the study information submitted to regulators.

Joanne Quinones, MD

Vice Chair Research, Dept OBGYN, Lehigh Valley Health Network

Responsibility Role PRINCIPAL_INVESTIGATOR

Locations

Explore where the study is taking place and check the recruitment status at each participating site.

Lehigh Valley Health Network

Allentown, Pennsylvania, United States

Site Status

Countries

Review the countries where the study has at least one active or historical site.

United States

Other Identifiers

Review additional registry numbers or institutional identifiers associated with this trial.

00000949

Identifier Type: -

Identifier Source: org_study_id

More Related Trials

Additional clinical trials that may be relevant based on similarity analysis.

Foley Catheter Induction
NCT05257187 WITHDRAWN NA
Outpatient Foley Cervix Priming
NCT02842879 COMPLETED NA