Are Comorbidities Related to Frequent Severe Exacerbations of AECOPD

NCT ID: NCT05504993

Last Updated: 2022-08-17

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

92 participants

Study Classification

OBSERVATIONAL

Study Start Date

2018-01-01

Study Completion Date

2022-01-01

Brief Summary

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INTRODUCTION: Relationship between comorbidities and COPD is two-sided. While the number of comorbidities increasing, the frequency of acute exacerbations of COPD (AECOPD) is increasing, too. Comorbidity indexes can be used for recognition of comorbidities while managing COPD patients. In the present study, it is aimed to compare comorbidity indexes such as Charlson Comorbidity Index, COMCOLD and COTE in the matter of exacerbation frequency.

METHOD: Subjects hospitalized for AECOPD, admitted to the study. Exacerbation severity, frequency, further exacerbations for a 1-year period in the follow-up period and CCI, COMCOLD and COTE scores were recorded. High and low comorbidity groups were compared for AECOPD frequency, severity, and further exacerbations.

Detailed Description

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Conditions

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Chronic Obstructive Lung Disease Acute Exacerbation of COPD Comorbidities and Coexisting Conditions

Study Design

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Observational Model Type

CASE_ONLY

Study Time Perspective

CROSS_SECTIONAL

Study Groups

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High comorbidity group

CCI equal or higher than 2 COTE equal or higher than 4 COMCOLD equal or higher than 4

Frequency of AECOPD

Intervention Type OTHER

No intervention has been applied. 92 COPD patients divided into 2 groups according to their comorbidity level. Than these groups were compared for their AECOPD frequency

Low comorbidity group

CCI lower than 2 COTE lower than 4 COMCOLD lower than 4

Frequency of AECOPD

Intervention Type OTHER

No intervention has been applied. 92 COPD patients divided into 2 groups according to their comorbidity level. Than these groups were compared for their AECOPD frequency

Interventions

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Frequency of AECOPD

No intervention has been applied. 92 COPD patients divided into 2 groups according to their comorbidity level. Than these groups were compared for their AECOPD frequency

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* COPD patients
* Admitted to the ward for AECOPD

Exclusion Criteria

* Not giving informed consent
* Unable to perform PFT
* Lost to follow-up
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Ankara University

OTHER

Sponsor Role lead

Responsible Party

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Deniz Doğan Mülazimoğlu

University Lecturer

Responsibility Role PRINCIPAL_INVESTIGATOR

Locations

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Ankara University Faculty of Medicine

Ankara, , Turkey (Türkiye)

Site Status

Countries

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Turkey (Türkiye)

Other Identifiers

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05-305-18

Identifier Type: -

Identifier Source: org_study_id

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