Project RESIST: Evaluating the Effects of Anti-smoking Inoculation Messages Among Young Adult Sexual Minority Women

NCT ID: NCT05499520

Last Updated: 2024-07-31

Study Results

Results available

Outcome measurements, participant flow, baseline characteristics, and adverse events have been published for this study.

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Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

2591 participants

Study Classification

INTERVENTIONAL

Study Start Date

2022-09-21

Study Completion Date

2023-08-15

Brief Summary

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Project RESIST is an R01 study funded by NCI focused on determining the effects of using culturally tailored inoculation approaches to increase resilience to tobacco marketing influences among young adult sexual minority women ages 18-30 and incorporates critical stakeholder inputs that support later adoption and implementation. The study team is utilizing formative research to design and pre-test anti-smoking messages and two national longitudinal online survey experiments.

Detailed Description

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This study will recruit 3000 young adult sexual minority women (SMW), ages 18-30 years, current smokers (n = 1500) and not current smokers (n = 1500). The study will determine the effects of varying the dose (single vs. multiple), and latency (immediate vs. delayed) of showing participants inoculation anti-smoking messages on smoking and quitting intentions. The study team hypothesize that the multiple exposures (vs. single), and delayed exposure (vs. immediate) will be associated with increased resistance to marketing, reduced smoking intention, and increased quitting intention. The study team will further explore the mechanisms of inoculation effects through emotions, beliefs, and attitudes towards tobacco companies. Participants will be asked to complete a baseline survey and then will receive an anti-smoking message in varying dosages based on the condition they are assigned with a control group receiving no message. Participants will then see a pro-smoking or threat message immediately, one week, or one month late, depending on the condition they were assigned.

Conditions

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Cigarette Smoking Behavior

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

FACTORIAL

Primary Study Purpose

PREVENTION

Blinding Strategy

SINGLE

Participants

Study Groups

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Currently Smoking, No Message Condition

Participants will receive no anti-smoking messages. They will receive the threat message during the baseline survey. Outcomes will be measured before and immediately after seeing the threat message, and at 1 month.

Group Type NO_INTERVENTION

No interventions assigned to this group

Currently Smoking, Single Message Immediate

Participants will receive a single anti-smoking message followed by the threat message during the baseline survey. Outcomes will be measured before seeing the anti-smoking message and threat message, immediately after seeing the threat message, and at 1 month.

Group Type EXPERIMENTAL

Culturally Tailored Anti-Smoking Messages

Intervention Type OTHER

Anti-smoking messages will be administered online via a Qualtrics survey.

Currently Smoking, Single Message 1 Week Delay

Participants will receive a single anti-smoking message during the baseline survey, followed by the threat message one week later in a separate survey. Outcomes will be measured before seeing the anti-smoking message at baseline, immediately after seeing the threat message at 1 week, and at 1 month.

Group Type EXPERIMENTAL

Culturally Tailored Anti-Smoking Messages

Intervention Type OTHER

Anti-smoking messages will be administered online via a Qualtrics survey.

Currently Smoking, Single Message 1 Month Delay

Participants will receive a single anti-smoking message during the baseline survey, followed by the threat message one month later in a separate survey. Outcomes will be measured before seeing the anti-smoking message at baseline, and immediately after seeing the threat message at 1 month.

Group Type EXPERIMENTAL

Culturally Tailored Anti-Smoking Messages

Intervention Type OTHER

Anti-smoking messages will be administered online via a Qualtrics survey.

Currently Smoking, Single Message 1 Month Delay, Repeated Exposure

Participants will receive a single anti-smoking message during the baseline survey, followed by the threat message one month later. Participants will also receive repeated exposures of a single anti-smoking message at 1, 2, and 3 weeks in separate surveys. Outcomes will be measured before seeing the anti-smoking message at baseline and immediately after seeing the threat message at 1 month.

Group Type EXPERIMENTAL

Culturally Tailored Anti-Smoking Messages

Intervention Type OTHER

Anti-smoking messages will be administered online via a Qualtrics survey.

Currently Smoking, Three Messages Immediate

Participants will receive three anti-smoking messages, followed by the threat message during the baseline survey. Outcomes will be measured before seeing the anti-smoking messages and threat message, immediately after seeing the threat message, and at 1 month.

Group Type EXPERIMENTAL

Culturally Tailored Anti-Smoking Messages

Intervention Type OTHER

Anti-smoking messages will be administered online via a Qualtrics survey.

Currently Smoking, Three Messages 1 Week Delay

Participants will receive three anti-smoking messages during the baseline survey, followed by the threat message one week later in a separate survey. Outcomes will be measured before seeing the anti-smoking messages at baseline, immediately after seeing the threat message at 1 week, and at 1 month.

Group Type EXPERIMENTAL

Culturally Tailored Anti-Smoking Messages

Intervention Type OTHER

Anti-smoking messages will be administered online via a Qualtrics survey.

Currently Smoking, Three Messages 1 Month Delay

Participants will receive three anti-smoking messages during the baseline survey, followed by the threat message one month later in a separate survey. Outcomes will be measured before seeing the anti-smoking messages at baseline, and immediately after seeing the threat message at 1 month.

Group Type EXPERIMENTAL

Culturally Tailored Anti-Smoking Messages

Intervention Type OTHER

Anti-smoking messages will be administered online via a Qualtrics survey.

Currently Smoking, Three Messages 1 Month Delay Repeat Exposure

Participants will receive three anti-smoking messages during the baseline survey, followed by the threat message one month later. Participants will also receive repeated exposures of three anti-smoking messages at 1, 2, and 3 weeks in separate surveys. Outcomes will be measured before seeing the anti-smoking messages at baseline and immediately after seeing the threat message at 1 month.

Group Type EXPERIMENTAL

Culturally Tailored Anti-Smoking Messages

Intervention Type OTHER

Anti-smoking messages will be administered online via a Qualtrics survey.

Not Currently Smoking, No Message Condition

Participants will receive no anti-smoking messages. They will receive the threat message during the baseline survey. Outcomes will be measured before and immediately after seeing the threat message, and at 1 month.

Group Type NO_INTERVENTION

No interventions assigned to this group

Not Currently Smoking, Single Message Immediate

Participants will receive a single anti-smoking message followed by the threat message during the baseline survey. Outcomes will be measured before seeing the anti-smoking message and threat message, immediately after seeing the threat message, and at 1 month.

Group Type EXPERIMENTAL

Culturally Tailored Anti-Smoking Messages

Intervention Type OTHER

Anti-smoking messages will be administered online via a Qualtrics survey.

Not Currently Smoking, Single Message 1 Week Delay

Participants will receive a single anti-smoking message during the baseline survey, followed by the threat message one week later in a separate survey. Outcomes will be measured before seeing the anti-smoking message at baseline, immediately after seeing the threat message at 1 week, and at 1 month.

Group Type EXPERIMENTAL

Culturally Tailored Anti-Smoking Messages

Intervention Type OTHER

Anti-smoking messages will be administered online via a Qualtrics survey.

Not Currently Smoking, Single Message 1 Month Delay

Participants will receive a single anti-smoking message during the baseline survey, followed by the threat message one month later in a separate survey. Outcomes will be measured before seeing the anti-smoking message at baseline, and immediately after seeing the threat message at 1 month.

Group Type EXPERIMENTAL

Culturally Tailored Anti-Smoking Messages

Intervention Type OTHER

Anti-smoking messages will be administered online via a Qualtrics survey.

Not Currently Smoking, Single Message 1 Month Delay, Repeated Exposure

Participants will receive a single anti-smoking message during the baseline survey, followed by the threat message one month later. Participants will also receive repeated exposures of a single anti-smoking message at 1, 2, and 3 weeks in separate surveys. Outcomes will be measured before seeing the anti-smoking message at baseline and immediately after seeing the threat message at 1 month.

Group Type EXPERIMENTAL

Culturally Tailored Anti-Smoking Messages

Intervention Type OTHER

Anti-smoking messages will be administered online via a Qualtrics survey.

Not Currently Smoking, Three Messages Immediate

Participants will receive three anti-smoking messages, followed by the threat message during the baseline survey. Outcomes will be measured before seeing the anti-smoking messages and threat message, immediately after seeing the threat message, and at 1 month.

Group Type EXPERIMENTAL

Culturally Tailored Anti-Smoking Messages

Intervention Type OTHER

Anti-smoking messages will be administered online via a Qualtrics survey.

Not Currently Smoking, Three Messages 1 Week Delay

Participants will receive three anti-smoking messages during the baseline survey, followed by the threat message one week later in a separate survey. Outcomes will be measured before seeing the anti-smoking messages at baseline, immediately after seeing the threat message at 1 week, and at 1 month.

Group Type EXPERIMENTAL

Culturally Tailored Anti-Smoking Messages

Intervention Type OTHER

Anti-smoking messages will be administered online via a Qualtrics survey.

Not Currently Smoking, Three Messages 1 Month Delay

Participants will receive three anti-smoking messages during the baseline survey, followed by the threat message one month later in a separate survey. Outcomes will be measured before seeing the anti-smoking messages at baseline, and immediately after seeing the threat message at 1 month.

Group Type EXPERIMENTAL

Culturally Tailored Anti-Smoking Messages

Intervention Type OTHER

Anti-smoking messages will be administered online via a Qualtrics survey.

Not Currently Smoking, Three Messages 1 Month Delay Repeat Exposure

Participants will receive three anti-smoking messages during the baseline survey, followed by the threat message one month later. Participants will also receive repeated exposures of three anti-smoking messages at 1, 2, and 3 weeks in separate surveys. Outcomes will be measured before seeing the anti-smoking messages at baseline and immediately after seeing the threat message at 1 month.

Group Type EXPERIMENTAL

Culturally Tailored Anti-Smoking Messages

Intervention Type OTHER

Anti-smoking messages will be administered online via a Qualtrics survey.

Interventions

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Culturally Tailored Anti-Smoking Messages

Anti-smoking messages will be administered online via a Qualtrics survey.

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* Ages 18-30
* Woman
* Identifies as a sexual minority (any sexual orientation other than heterosexual)
* Lives in the United States
* Able to take surveys in English

Exclusion Criteria

* Under 18 or older than 30
* Men
* Heterosexual
* Lives outside the United States
* Unable to take the survey in English
Minimum Eligible Age

18 Years

Maximum Eligible Age

30 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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National Cancer Institute (NCI)

NIH

Sponsor Role collaborator

Harvard School of Public Health (HSPH)

OTHER

Sponsor Role collaborator

Stanford University

OTHER

Sponsor Role collaborator

Dana-Farber Cancer Institute

OTHER

Sponsor Role collaborator

Fenway Community Health

OTHER

Sponsor Role collaborator

Abramson Cancer Center at Penn Medicine

OTHER

Sponsor Role lead

Responsible Party

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Andy Tan

Associate Professor

Responsibility Role PRINCIPAL_INVESTIGATOR

Locations

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University of Pennsylvania

Philadelphia, Pennsylvania, United States

Site Status

Countries

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United States

Provided Documents

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Document Type: Study Protocol and Statistical Analysis Plan

View Document

Other Identifiers

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R01CA237670

Identifier Type: NIH

Identifier Source: secondary_id

View Link

11022

Identifier Type: -

Identifier Source: org_study_id

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