The Effect of Gallstone Characteristics for the Severity of Gallstone Pancreatitis

NCT ID: NCT05498961

Last Updated: 2023-09-26

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

301 participants

Study Classification

OBSERVATIONAL

Study Start Date

2022-08-10

Study Completion Date

2023-09-24

Brief Summary

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The purpose of this study was to determine the effect of gallstone characteristics for the severity of acute gallstone pancreatitis (GSP)

Detailed Description

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The timing of cholecystectomy is closely related to the severity of acute gallstone pancreatitis (GSP). The effect of gallstone characteristics (including stone size, number, etc.) for the severity of GSP are currently unknown.

Conditions

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Acute Gallstone Pancreatitis

Study Design

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Observational Model Type

COHORT

Study Time Perspective

RETROSPECTIVE

Interventions

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Gallstone characteristics

stone size, number, the thickness

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* Acute gallstone pancreatitis (GSP) patients.

Exclusion Criteria

* Pancreatitis with bile duct stones, trauma, drugs, and surgery;
* Recurrent gallstone pancreatitis;
* Combined with other malignant tumors, such as liver cancer, cholangiocarcinoma, pancreatic cancer, gastric cancer, Hematologic tumor, and lymphoma;
* Previous hepatobiliary and pancreatic surgery, Organ transplantation;
* Intestinal obstruction or other obstructive diseases;
* Chronic pancreatitis or pancreatic duct stones;
* Thrombotic disease;
* Alcoholic pancreatitis and hyperlipidemia pancreatitis.
Minimum Eligible Age

18 Years

Maximum Eligible Age

90 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Hepatopancreatobiliary Surgery Institute of Gansu Province

OTHER

Sponsor Role lead

Responsible Party

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Wenbo Meng

Professor of surgery

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Wenbo Meng, M.D.,Ph.D

Role: PRINCIPAL_INVESTIGATOR

LanZhou University

Locations

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Hepatopancreatobiliary Surgery Institute of Gansu Province

Lanzhou, Gansu, China

Site Status

Countries

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China

References

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Yadav D, Lowenfels AB. The epidemiology of pancreatitis and pancreatic cancer. Gastroenterology. 2013 Jun;144(6):1252-61. doi: 10.1053/j.gastro.2013.01.068.

Reference Type BACKGROUND
PMID: 23622135 (View on PubMed)

Boxhoorn L, Voermans RP, Bouwense SA, Bruno MJ, Verdonk RC, Boermeester MA, van Santvoort HC, Besselink MG. Acute pancreatitis. Lancet. 2020 Sep 5;396(10252):726-734. doi: 10.1016/S0140-6736(20)31310-6.

Reference Type BACKGROUND
PMID: 32891214 (View on PubMed)

Ma Y, Yue P, Zhang J, Yuan J, Liu Z, Chen Z, Zhang H, Zhang C, Zhang Y, Dong C, Lin Y, Liu Y, Li S, Meng W. Early prediction of acute gallstone pancreatitis severity: a novel machine learning model based on CT features and open access online prediction platform. Ann Med. 2024 Dec;56(1):2357354. doi: 10.1080/07853890.2024.2357354. Epub 2024 May 30.

Reference Type DERIVED
PMID: 38813815 (View on PubMed)

Other Identifiers

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acute gallstone pancreatitis

Identifier Type: -

Identifier Source: org_study_id

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