Bio-Repository of DNA in Stroke: an Epidemiological and Genetic Study

NCT ID: NCT05491824

Last Updated: 2022-08-08

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Total Enrollment

7500 participants

Study Classification

OBSERVATIONAL

Study Start Date

2005-06-11

Study Completion Date

2023-12-31

Brief Summary

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The Bio-Repository of DNA in Stroke (BRAINS) recruits all subtypes of stroke as well as controls from two different continents, Europe and Asia. Subjects recruited from the United Kingdom (UK) will include stroke patients of European ancestry as well as British South Asians. Stroke subjects from South Asia will be recruited from India and Sri Lanka. Subjects are also recruited in Qatar. South Asian cases will also have control subjects recruited.

Detailed Description

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Conditions

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Stroke Stroke, Ischemic Stroke Hemorrhagic

Study Design

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Observational Model Type

CASE_CONTROL

Study Time Perspective

CROSS_SECTIONAL

Study Groups

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Stroke

No interventions assigned to this group

Non-stroke

No interventions assigned to this group

Eligibility Criteria

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Inclusion Criteria

* Patients should be aged \> 18 years at the time of enrolment.
* Diagnosis of haemorrhagic or ischemic stroke using World Health Organization guidelines confirmed by clinical examination and imaging (CT or MRI).
* All patients with cerebral arteriovascular malformations and aneurysms.
* South Asian or Caucasian ethnic backgrounds.
* Patient or relative written informed consent.


* Patients should be aged \> 18 years at the time of enrolment.
* No previous history of stroke.
* able to provide written consent.

Exclusion Criteria

* Unable to provide consent themselves or through surrogate.
* Stroke not defined on CT or MRI.

Controls
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Royal Holloway University

OTHER

Sponsor Role lead

Responsible Party

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Pankaj Sharma, MD PhD

Professor

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Pankaj Sharma, MD PhD

Role: PRINCIPAL_INVESTIGATOR

Royal Holloway University

Locations

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Imperial College London

London, , United Kingdom

Site Status RECRUITING

Countries

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United Kingdom

Central Contacts

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Pankaj Sharma, MD PhD

Role: CONTACT

01784434455

Facility Contacts

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Pankaj Sharma, MD PhD

Role: primary

Other Identifiers

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BRAINS

Identifier Type: -

Identifier Source: org_study_id

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