Best Revascularisation Approach for Posterior Circulation Strokes With Isolated Vertebral Artery Occlusions
NCT ID: NCT05503212
Last Updated: 2023-08-14
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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COMPLETED
682 participants
OBSERVATIONAL
2003-01-01
2023-08-09
Brief Summary
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In the absence of RCT, observational data with appropriate statistical methods may give indications on benefits and harms of treating neglected stroke situations like acute vertebral occlusion. Results may also lay the basis for prospective studies, such as randomized clinical trials.
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Detailed Description
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Conditions
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Study Design
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COHORT
RETROSPECTIVE
Study Groups
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AIS and isolated VAO
Patients with acute ischemic stroke (AIS) and concomitant isolated intracranial and/or extracranial vertebral artery occlusion (VAO)
Conservative treatment (CT)
Best medical treatment without intravenous thrombolysis nor endovascular thrombectomy
Intravenous thrombolysis (IVT)
Best medical treatment with intravenous thrombolysis but without endovascular thrombectomy
Endovascular thrombectomy (EVT) ± intravenous thrombolysis (IVT)
Best medical treatment with endovascular thrombectomy with or without intravenous thrombolysis
Interventions
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Conservative treatment (CT)
Best medical treatment without intravenous thrombolysis nor endovascular thrombectomy
Intravenous thrombolysis (IVT)
Best medical treatment with intravenous thrombolysis but without endovascular thrombectomy
Endovascular thrombectomy (EVT) ± intravenous thrombolysis (IVT)
Best medical treatment with endovascular thrombectomy with or without intravenous thrombolysis
Eligibility Criteria
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Inclusion Criteria
* Presence of uni- or bilateral VAO (intracranial and/or extracranial) on at least one initial imaging study (CTA, MRA, DSA)
* IVT, EVT or bridging-treated stroke patients between 01.01.2003 and 31.12.2021
* ≥ 18 years old
Exclusion Criteria
* Presence of a more distal occlusion in the pc (tandem occlusion/multilevel poster circulation occlusions)
* Previously known chronic occlusion of the any segment of the vertebral artery/arteries
* Local ethical/legal conditions in participating center not fulfilled
18 Years
ALL
No
Sponsors
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Asan Medical Center
OTHER
St John of God Hospital, Vienna
OTHER
Medical University Innsbruck
OTHER
Hospital Vall d'Hebron
OTHER
University Hospital, Basel, Switzerland
OTHER
Clinical Centre of Serbia
OTHER
Charite University, Berlin, Germany
OTHER
Insel Gruppe AG, University Hospital Bern
OTHER
Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico
OTHER
Boston Medical Center
OTHER
Università degli Studi di Brescia
OTHER
The Cooper Health System
OTHER
University Hospital Carl Gustav Carus
OTHER
Duke University
OTHER
University Hospital, Geneva
OTHER
Hadassah Medical Organization
OTHER
Sahlgrenska University Hospital
OTHER
Universitätsklinikum Hamburg-Eppendorf
OTHER
Helsinki University Central Hospital
OTHER
The University of Texas Health Science Center, Houston
OTHER
University Hospital, Lille
OTHER
Hospital de Egas Moniz
OTHER
Neurocenter of Southern Switzerland
OTHER
Spectrum Health Hospitals
OTHER
Azienda Ospedaliero-Universitaria di Modena
OTHER
Ludwig-Maximilians - University of Munich
OTHER
Azienda USL Reggio Emilia - IRCCS
OTHER_GOV
University of Zurich
OTHER
Centre Hospitalier Universitaire Vaudois
OTHER
Responsible Party
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Dr. med. Alexander Salerno, MD
Clinical Researcher, Principal Investigator
Principal Investigators
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Dr. med. Alexander Salerno, MD
Role: PRINCIPAL_INVESTIGATOR
CHUV
Locations
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Centre Hospitalier Universitaire Vaudois
Lausanne, Canton of Vaud, Switzerland
Countries
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Other Identifiers
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Stroke-VAO
Identifier Type: -
Identifier Source: org_study_id
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