Alteration of Thrombelastography and Coagulation Function in Patients Undergoing Total Knee Arthroplasty With Intra-articular Tranexamic Acid Administration
NCT ID: NCT05490160
Last Updated: 2022-08-05
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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UNKNOWN
54 participants
OBSERVATIONAL
2022-08-05
2022-08-28
Brief Summary
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Detailed Description
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Conditions
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Study Design
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CASE_ONLY
RETROSPECTIVE
Study Groups
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Tranexamic acid group
During the total knee arthroplasty, the patients received a 2-g retrograde injection of tranexamic acid through the drain after closure, with subsequent clamping of the drain for 6 hours.
Tranexamic acid
During the total knee arthroplasty, the patients received a 2-g retrograde injection of tranexamic acid through the drain after closure, with subsequent clamping of the drain for 6 hours.
Non-tranexamic acid group
During the total knee arthroplasty, the patients did not receive tranexamic acid administration.
No interventions assigned to this group
Interventions
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Tranexamic acid
During the total knee arthroplasty, the patients received a 2-g retrograde injection of tranexamic acid through the drain after closure, with subsequent clamping of the drain for 6 hours.
Eligibility Criteria
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Inclusion Criteria
* Normal pre-operative coagulation function;
* Complete surgery document, transfusion document and relative blood test.
Exclusion Criteria
* Abnormal pre-operative coagulation function caused by some diseases such as hepatic inadequacy, thrombocytopenia et al.
* Incomplete documents.
ALL
No
Sponsors
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RenJi Hospital
OTHER
Responsible Party
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Principal Investigators
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Lin Du
Role: STUDY_CHAIR
RenJi Hospital
Central Contacts
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Other Identifiers
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IIT-2022-0059
Identifier Type: -
Identifier Source: org_study_id
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