Thromboelastogram During Total Knee Replacement

NCT ID: NCT02373969

Last Updated: 2016-04-06

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

30 participants

Study Classification

OBSERVATIONAL

Study Start Date

2011-08-31

Study Completion Date

2012-01-31

Brief Summary

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Verify the changes in coagulation system during total knee replacement surgery with tranexamic acid single bolus infusion.

Detailed Description

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The study was set to reveal changes in the coagulation and fibrinolytic systems during total knee surgery and especially during tourniquet placement, tourniquet removal and revascularization of ischemic limb, after tranexamic acid single bolus infusion, and at post operative day 1.

Conditions

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Orthopedic Procedures, Tranexamic Acid

Study Design

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Observational Model Type

CASE_ONLY

Study Time Perspective

PROSPECTIVE

Eligibility Criteria

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Inclusion Criteria

* Osteoarthrosis
* TKR operation elective
* ASA I-III

Exclusion Criteria

* TKR due to any reason but osteoarthrosis
* known coagulation problems
* platelets \< 100,000/DcL
* Hb \< 12 g%
* past thrombo-embolic event
* treatment with aspiring during last week
* treatment with NSAID's during last 48 hours
* malignancy
* known allergy to tranexamic acid
* general anesthesia
Minimum Eligible Age

18 Years

Maximum Eligible Age

75 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Rambam Health Care Campus

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Other Identifiers

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TEG-099-11

Identifier Type: -

Identifier Source: org_study_id

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