Percutaneous Plug-based Femoral Arteriotomy Closure Device Use in Surgery for Acute Type A Aortic Disection

NCT ID: NCT05482555

Last Updated: 2023-01-04

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

171 participants

Study Classification

OBSERVATIONAL

Study Start Date

2017-01-31

Study Completion Date

2022-06-30

Brief Summary

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A single-center prospective study. Patients undergoing surgery for acute type A aortic dissection with femoral arterial cannulation between 2017 and 2022 at the Karolinska University Hospital in Stockholm, Sweden are eligible. Femoral cannulation was performed either with surgical cut-down and arterial puncture under direct vision or percutaneously with planned percutaneous arteriotomy closed using a plug-based arteriotomy closure device (MANTA, Essential Medical Inc., Malvern, Pennsylvania). Data regarding preoperative clinical characteristics and operative details were obtained by medical records review.

Detailed Description

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Conditions

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Aortic Dissection

Study Design

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Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Study Groups

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Intervention/treatment Surgical cut-down and arterial puncture under direct vision

Surgical cut-down and arterial puncture under direct vision.

Surgical cut-down and arterial puncture under direct vision

Intervention Type PROCEDURE

Surgical cut-down and arterial puncture under direct vision.

Percutaneous arteriotomy closed with closure device

Percutaneous arteriotomy closed using a plug-based arteriotomy closure device (MANTA, Essential Medical Inc., Malvern, Pennsylvania).

Percutaneous arteriotomy closed using a plug-based arteriotomy closure device

Intervention Type PROCEDURE

Percutaneous arteriotomy closed using a plug-based arteriotomy closure device (MANTA, Essential Medical Inc., Malvern, Pennsylvania).

Interventions

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Percutaneous arteriotomy closed using a plug-based arteriotomy closure device

Percutaneous arteriotomy closed using a plug-based arteriotomy closure device (MANTA, Essential Medical Inc., Malvern, Pennsylvania).

Intervention Type PROCEDURE

Surgical cut-down and arterial puncture under direct vision

Surgical cut-down and arterial puncture under direct vision.

Intervention Type PROCEDURE

Eligibility Criteria

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Inclusion Criteria

* Operated for acute type A aortic dissection between 2017 and 2022 at the Karolinska University Hospital in Stockholm, Sweden.

Exclusion Criteria

* Non-femoral arterial cannulation
* Concomitant femoro-femoral bypass
* Conversion to ECMO with arterial inflow in the previously cannulated femoral artery
* Death within 30 days from procedure
* Loss to follow-up
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Karolinska University Hospital

OTHER

Sponsor Role lead

Responsible Party

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Magnus Dalén

MD, PhD

Responsibility Role PRINCIPAL_INVESTIGATOR

Locations

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Department of Cardiothoracic Surgery, Karolinska University Hospital

Stockholm, , Sweden

Site Status

Countries

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Sweden

Other Identifiers

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MANTA-ATAAD

Identifier Type: -

Identifier Source: org_study_id

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