Neuropsychological Assessment Of The Oldest-Old Population.(NEUROPSIC-GR)
NCT ID: NCT05481749
Last Updated: 2025-06-26
Study Results
Results pending
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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Recruitment Status
RECRUITING
Total Enrollment
120 participants
Study Classification
OBSERVATIONAL
Study Start Date
2023-02-14
Study Completion Date
2026-03-31
Brief Summary
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Neuropsychological tests currently considered to evaluate the cognitive performance of the oldest-old population (more than 80 years) are not adapted to this group population. This trial aims to determine the normal limits for this group population of a set of 18 neuropsychological test. Results may improve the diagnostic cognitive evaluation of this population.
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Detailed Description
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120 subjects more than 80y old (non-institutionalized) grouped in 4 age categories (80-84, 85-89, 90-94, 95 or more) will be evaluated through 18 neuropsychological tests (usually considered at Memory Clinics).
Subjects will be recruited from 5 Primary Care Centers by a random selection method (stratified by age group).
Normal limits will be defined by the percentiles of test punctuation. Previously, punctuation will be adjusted by age and education level by lineal regression.
Subjects will be recruited from 5 Primary Care Centers by a random selection method (stratified by age group).
Normal limits will be defined by the percentiles of test punctuation. Previously, punctuation will be adjusted by age and education level by lineal regression.
Conditions
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Dementia
Cognition Disorders in Old Age
Study Design
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Observational Model Type
CASE_ONLY
Study Time Perspective
CROSS_SECTIONAL
Study Groups
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Neuropsico-Ger
People aged 80 or more years, non-institutionalized, and without pathologies potentially affecting cognitive status.
No interventions assigned to this group
Eligibility Criteria
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Inclusion Criteria
* 80 or more years old
* Residence at Comarca del Garraf
* Able to be transfered to study center
* Sufficient reading and writing capacity to carry out the neuropsychological tests, at the evaluator's discretion.
* Residence at Comarca del Garraf
* Able to be transfered to study center
* Sufficient reading and writing capacity to carry out the neuropsychological tests, at the evaluator's discretion.
Exclusion Criteria
* Patient at end-of-life situation or with a very short life expectancy (days-weeks).
* Hospital admission in the previous 3 months.
* History of relevant mental illness: major depression, psychosis, bipolar disorder, obsessive-compulsive disorder.
* Disease of the central nervous system with possible cognitive impairment: Parkinson's disease, multiple sclerosis, brain tumor, stroke with cognitive impairment, epilepsy, severe traumatic brain injury.
* History of alcoholism or substance abuse.
* Severe sensory deficit that prevents performing neuropsychological tests, at the discretion of the evaluator.
* Positive Shortened Spanish Informant Questionnaire for Cognitive Decline in the Elderly questionnaire (SS-IQCODE) or Lobo's Cognitive Mini-examination Test (spanish adaptation of Minimental of Folstein test) with a score \< 23 (20 in people with low schooling or illiteracy).
* Dementia criteria according to the Diagnostic and Statistical Manual of Mental Disorders IV.
* Hospital admission in the previous 3 months.
* History of relevant mental illness: major depression, psychosis, bipolar disorder, obsessive-compulsive disorder.
* Disease of the central nervous system with possible cognitive impairment: Parkinson's disease, multiple sclerosis, brain tumor, stroke with cognitive impairment, epilepsy, severe traumatic brain injury.
* History of alcoholism or substance abuse.
* Severe sensory deficit that prevents performing neuropsychological tests, at the discretion of the evaluator.
* Positive Shortened Spanish Informant Questionnaire for Cognitive Decline in the Elderly questionnaire (SS-IQCODE) or Lobo's Cognitive Mini-examination Test (spanish adaptation of Minimental of Folstein test) with a score \< 23 (20 in people with low schooling or illiteracy).
* Dementia criteria according to the Diagnostic and Statistical Manual of Mental Disorders IV.
Minimum Eligible Age
80 Years
Eligible Sex
ALL
Accepts Healthy Volunteers
No
Sponsors
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Centro de Salud Vilanova i la Geltrú 2 Jaume I, Barcelona, Spain
UNKNOWN
Sponsor Role
collaborator
Centro de Salud Vilanova i la Geltrú 3 Baix A Mar, Barcelona, Spain
UNKNOWN
Sponsor Role
collaborator
Centro de Salud Les Roquetes-Sant Pere de Ribes, Barcelona, Spain
UNKNOWN
Sponsor Role
collaborator
Gerència Territorial Metropolitana Sud, Alt Penedès i Garraf, Barcelona, Spain
UNKNOWN
Sponsor Role
collaborator
Centro de Salud Sant Pere de Ribes, Barcelona, Spain
UNKNOWN
Sponsor Role
collaborator
Centro de Salud Vilanova i la Geltrú 1 Sant Joan, Barcelona, Spain
UNKNOWN
Sponsor Role
collaborator
Centro de Salud Sitges, Barcelona, Spain
UNKNOWN
Sponsor Role
collaborator
Consorci Sanitari de l'Alt Penedès i Garraf
OTHER
Sponsor Role
lead
Responsible Party
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Responsibility Role
SPONSOR
Principal Investigators
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César Gálvez-Barrón, Ph.D.
Role: PRINCIPAL_INVESTIGATOR
Consorci Sanitari de l'Alt Penedès i Garraf
Locations
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Centro de Salud Les Roquetes-Sant Pere de Ribes
Sant Pere de Ribes, Barcelona, Spain
Site Status
RECRUITING
Centros de Salud Sitges
Sitges, Barcelona, Spain
Site Status
RECRUITING
Centro de Salud Vilanova i la Geltrú 1
Vilanova i la Geltrú, Barcelona, Spain
Site Status
RECRUITING
Centro de Salud Vilanova i la Geltrú 2 Jaume I
Vilanova i la Geltrú, Barcelona, Spain
Site Status
RECRUITING
Centro de Salud Vilanova i la Geltrú 3 Baix A Mar
Vilanova i la Geltrú, Barcelona, Spain
Site Status
RECRUITING
Centro de Salud Sant Pere de Ribes
Sant Pere de Ribes, Barcelone, Spain
Site Status
RECRUITING
Countries
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Spain
Central Contacts
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Facility Contacts
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References
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Other Identifiers
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CSAPG-23v2
Identifier Type: -
Identifier Source: org_study_id
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