Sudden Sensorineural Hearing Loss in Wonju Severance Christian Hospital

NCT ID: NCT05474963

Last Updated: 2025-03-26

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

RECRUITING

Total Enrollment

1000 participants

Study Classification

OBSERVATIONAL

Study Start Date

2021-07-14

Study Completion Date

2035-12-31

Brief Summary

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This study is to build a cohort of sudden sensorineural hearing loss (SSNHL) patients. When the patient visited the Department of otolaryngology clinic for hearing loss, we can diagnose the SSNHL following the result of pure tone audiometry and the history of the patient. The cohort is a system that tracks the hearing recovery status, timing, and degree of recovery of patients who received cocktail therapy with or without high-dose steroids, vasodilators, antiviral agents, and intratympanic steroid injections, satellite ganglion block, and hyperbaric oxygen therapy.

Detailed Description

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Conditions

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SSNHL(Sudden Sensory Neural Hearing Loss) Sudden Hearing Loss Hearing Loss, Idiopathic Sudden Sensorineural Hearing Loss, Sudden

Study Design

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Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Study Groups

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SSNHL treated with WSCH protocol

SSNHL treated with WSCH protocol

No interventions assigned to this group

Eligibility Criteria

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Inclusion Criteria

* Adult patients over 20 years of age
* A patient who visited Wonju Severance Christian Hospital, Department of Otolaryngology and was diagnosed with sudden hearing loss as it was confirmed that hearing loss of 30dBHL or more occurred within 3 days at three consecutive frequencies in a pure tone audiometry test.
* Those who have fully explained the purpose and content of the study and voluntarily agreed to the written consent

Exclusion Criteria

* If the patients do not want to or do not fill out the consent form
* If treatment is started for sudden hearing loss, but the possibility of other inner ear diseases including Meniere's disease is suspected due to repeated hearing loss, repeated recovery, dizziness, tinnitus, etc.
* Other cases where it is judged difficult to carry out the clinical trial due to the judgment of the person in charge of the above clinical trial
Minimum Eligible Age

20 Years

Maximum Eligible Age

100 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Wonju Severance Christian Hospital

OTHER

Sponsor Role lead

Responsible Party

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Tae Hoon Kong, MD, PhD

Assistant Professor

Responsibility Role PRINCIPAL_INVESTIGATOR

Locations

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Yonsei University Wonju Severance Christian Hospital

Wŏnju, Gangwon-do, South Korea

Site Status RECRUITING

Countries

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South Korea

Central Contacts

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Tae Hoon Kong, MD, PhD

Role: CONTACT

+821044650635

Facility Contacts

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Tae Hoon Kong, MD, PhD

Role: primary

+821044650635

References

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Chandrasekhar SS, Tsai Do BS, Schwartz SR, Bontempo LJ, Faucett EA, Finestone SA, Hollingsworth DB, Kelley DM, Kmucha ST, Moonis G, Poling GL, Roberts JK, Stachler RJ, Zeitler DM, Corrigan MD, Nnacheta LC, Satterfield L. Clinical Practice Guideline: Sudden Hearing Loss (Update). Otolaryngol Head Neck Surg. 2019 Aug;161(1_suppl):S1-S45. doi: 10.1177/0194599819859885.

Reference Type BACKGROUND
PMID: 31369359 (View on PubMed)

Moon IS, Kim J, Lee SY, Choi HS, Lee WS. How long should the sudden hearing loss patients be followed after early steroid combination therapy? Eur Arch Otorhinolaryngol. 2009 Sep;266(9):1391-5. doi: 10.1007/s00405-009-0932-9. Epub 2009 Mar 13.

Reference Type BACKGROUND
PMID: 19283405 (View on PubMed)

Moon IS, Lee JD, Kim J, Hong SJ, Lee WS. Intratympanic dexamethasone is an effective method as a salvage treatment in refractory sudden hearing loss. Otol Neurotol. 2011 Dec;32(9):1432-6. doi: 10.1097/MAO.0b013e318238fc43.

Reference Type BACKGROUND
PMID: 22089956 (View on PubMed)

Rhee TM, Hwang D, Lee JS, Park J, Lee JM. Addition of Hyperbaric Oxygen Therapy vs Medical Therapy Alone for Idiopathic Sudden Sensorineural Hearing Loss: A Systematic Review and Meta-analysis. JAMA Otolaryngol Head Neck Surg. 2018 Dec 1;144(12):1153-1161. doi: 10.1001/jamaoto.2018.2133.

Reference Type BACKGROUND
PMID: 30267033 (View on PubMed)

Park SM, Han C, Lee JW, Kong TH, Seo YJ. Does Herpes Virus Reactivation Affect Prognosis in Idiopathic Sudden Sensorineural Hearing Loss? Clin Exp Otorhinolaryngol. 2017 Mar;10(1):66-70. doi: 10.21053/ceo.2016.00360. Epub 2016 Jul 27.

Reference Type BACKGROUND
PMID: 27459199 (View on PubMed)

Other Identifiers

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WSCH-ENT-SSNHL-01

Identifier Type: -

Identifier Source: org_study_id

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