Electroclinical Features of Sudden Unexpected Death in Epilepsy (SUDEP) : a Multi-center Observational Study

NCT ID: NCT05423990

Last Updated: 2024-01-18

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

ENROLLING_BY_INVITATION

Total Enrollment

30 participants

Study Classification

OBSERVATIONAL

Study Start Date

2022-04-01

Study Completion Date

2024-04-01

Brief Summary

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Sudden unexpected death in epilepsy (SUDEP) is regarded as a leading cause of premature death in epilepsy patients. We aim to capture the whole process of SUDEP and near-SUDEP occurrence in patients with epilepsy, and expolre video-electroencephalograph (V-EEG) changes and marker. A Chinese multicenter study was carried out to determine electroencephalo-graph marker related to SUDEP to provide a scientific basis for the prevention of SUDEP in patients with epilepsy.

Detailed Description

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Conditions

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Sudden Unexpected Death in Epilepsy Near-Sudden Unexpected Death in Epilepsy

Study Design

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Observational Model Type

CASE_ONLY

Study Time Perspective

PROSPECTIVE

Interventions

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Video-Electroencephalography

Three types of video EEG monitoring equipment produced by Nicolet, Bio-logic and Nihon Kohden were used to collect data in the multi-center. The 19-lead recording electrode was placed according to the international 10-20 system, and the average lead was used. The recording time was 24h. All patients underwent eyes open and closed test, intermittent photic stimulation and hyperventilation induction test.

Intervention Type DIAGNOSTIC_TEST

Eligibility Criteria

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Inclusion Criteria

* Patients with epilepsy who meet SUDEP or near-SUDEP diagnosis,
* Giving written informed consent to participate in the study from relatives or caregivers.

Exclusion Criteria

* Refusing to recruitment from relatives or caregivers.
Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Liu Yonghong

OTHER

Sponsor Role lead

Responsible Party

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Liu Yonghong

professor

Responsibility Role SPONSOR_INVESTIGATOR

Locations

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Liu Yonghong

Xi'an, Shaanxi, China

Site Status

Countries

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China

Other Identifiers

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KY20222037-C-1

Identifier Type: -

Identifier Source: org_study_id

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