Stressor-evoked Brain and Cardiovascular Responses to Acute Psychological Stress

NCT ID: NCT05413512

Last Updated: 2025-06-24

Study Results

Results available

Outcome measurements, participant flow, baseline characteristics, and adverse events have been published for this study.

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Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

170 participants

Study Classification

INTERVENTIONAL

Study Start Date

2020-03-02

Study Completion Date

2021-09-30

Brief Summary

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The present study will examine cardiovascular, metabolic, and neural responses to acute psychological stress using a cross-sectional approach.

Detailed Description

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All participants in this study will undergo an acute psychological stress paradigm, consisting of two acute psychological stress tasks (MSIT and Stoop). There is no formal randomization since al participants are randomized to undergo the acute psychological stress tasks.

Conditions

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Acute Psychological Stress

Study Design

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Allocation Method

NA

Intervention Model

SINGLE_GROUP

Primary Study Purpose

BASIC_SCIENCE

Blinding Strategy

NONE

Study Groups

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Acute psychological stress task (MSIT; Stroop)

Multi-source interference task (MSIT; Stroop)

Group Type EXPERIMENTAL

Acute psychological stress

Intervention Type OTHER

Experimental: Acute psychological stress Two, acute-psychological stress tasks known to reliably elicit a cardiovascular responses (Multi-source interference task; Stroop).

Interventions

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Acute psychological stress

Experimental: Acute psychological stress Two, acute-psychological stress tasks known to reliably elicit a cardiovascular responses (Multi-source interference task; Stroop).

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* 18-30 years old

Exclusion Criteria

* Chronic medical or neurological condition
* Pregnant
* Current illness or infection
* Any condition that would prohibit engaging in physical exercise
* Any metal implants in body
* Claustrophobia
Minimum Eligible Age

18 Years

Maximum Eligible Age

30 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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National Heart, Lung, and Blood Institute (NHLBI)

NIH

Sponsor Role collaborator

Baylor University

OTHER

Sponsor Role lead

Responsible Party

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Annie Ginty

Assistant Professor

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Annie Ginty, PhD

Role: PRINCIPAL_INVESTIGATOR

Baylor University

Locations

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Baylor University

Waco, Texas, United States

Site Status

Countries

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United States

Provided Documents

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Document Type: Study Protocol and Statistical Analysis Plan

View Document

Other Identifiers

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K01HL145021

Identifier Type: NIH

Identifier Source: secondary_id

View Link

1437575

Identifier Type: -

Identifier Source: org_study_id

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