Chiropractic T Cell Study

NCT ID: NCT05412602

Last Updated: 2025-02-10

Basic Information

• Recruitment Status: COMPLETED
• Clinical Phase: NA
• Total Enrollment: 38 participants
• Study Classification: INTERVENTIONAL
• Study Start Date: 2022-07-25
• Study Completion Date: 2023-12-31

Brief Summary

Some studies suggest that specific chiropractic care (techniques known as "spinal manipulation therapy") can have benefits to the immune system but studies are scarce, sample sizes small, and methodology and analyses often not of the highest scientific standards. The investigators will example how 36 sessions of chiropractic care over 9-12 weeks can impact immune cell function using a randomized clinical trial design.

Conditions

Intervention; Waitlist Control

Study Design

• Allocation Method: RANDOMIZED
• Intervention Model: PARALLEL
• Primary Study Purpose: BASIC_SCIENCE
• Blinding Strategy: SINGLE

Study Groups

Intervention

experimental group will receive 36 chiropractic treatments designed to correct vertebral subluxation over \~12 weeks

Group Type: EXPERIMENTAL

full spine corrective protocol

Intervention Type: PROCEDURE

36 chiropractic adjustments over 12 weeks (3 visits per week) with in office spinal traction on the 3D Denneroll Traction Table, as well as supplemental home exercises

waitlist control

waitlist control will receive no chiropractic interventions and will be reminded that to successfully complete their condition, they do not seek alternative chiropractic treatments

Group Type: NO_INTERVENTION

No interventions assigned to this group

Interventions

full spine corrective protocol

36 chiropractic adjustments over 12 weeks (3 visits per week) with in office spinal traction on the 3D Denneroll Traction Table, as well as supplemental home exercises

Intervention Type: PROCEDURE

Eligibility Criteria

Inclusion Criteria

• Must be between the ages of 18-70.
• Must exhibit vertebral subluxation as measured by a misalignment between one or more vertebrae in relation to normal spinal alignment.
• Have not been sick for the past 3 weeks (immune function).
• Non-smoker.
• Must be able to fast for 10-12 hours.

Exclusion Criteria

• To have had a chiropractic intervention within the past 6 months.
• To have a condition that may limit the ability to apply a high velocity, low amplitude (HVLA) thrust to the spine such as but not limited to ligament damage, reduced bone density, or other factors that weaken the body's ability to withstand reasonable care (bone cancer, fractures, osteoporosis, etc.)
• To have excessive scoliotic curvature of the spine (> 30º) as measured by identifying the first vertebrae, and the most laterally displaced vertebrae that exhibits tilt below it.

• Minimum Eligible Age: 18 Years
• Maximum Eligible Age: 70 Years
• Eligible Sex: ALL
• Accepts Healthy Volunteers: Yes

Sponsors

University of British Columbia

OTHER

Sponsor Role: lead

Responsible Party

Jonathan Little

Associate Professor

Responsibility Role: PRINCIPAL_INVESTIGATOR

Locations

University of British Columbia Okanagan

Kelowna, British Columbia, Canada

Countries

Canada

Other Identifiers

H21-00643

Identifier Type: -

Identifier Source: org_study_id