The Effectiveness of Low Level Laser Therapy on Particular Joint Points and Acupuncture Points on Knee Joints in Grade III Knee Osteoarthritis

NCT ID: NCT05403931

Last Updated: 2023-05-17

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Clinical Phase

NA

Total Enrollment

50 participants

Study Classification

INTERVENTIONAL

Study Start Date

2022-04-30

Study Completion Date

2023-09-30

Brief Summary

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LLLT is in use to treat different musculoskeletal condition. Osteoarthritis is one of the conditions needing LLLT for therapeutic effects. LLLT has been used in different previous studies using different points on joint and also on acupuncture points. This study is going to compare the effectiveness of LLLT on both points. Omega xp device is going to be used in this study.

Detailed Description

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LLLT is a non-invasive modality to treat variety of musculoskeletal conditions. Photobiomodulation has been studies for last two decades in different perspectives and on different musculoskeletal condition. Studies suggest profound results due to effect of LLLT at the cellular level. Osteoarthritis is one of the most common debilitating musculoskeletal condition affecting people worldwide. Statistics indicate an increase in this debilitating condition in future. Knee OA is more common amongst other OA of the body. LLLT has been used in previous studies to see the impact on pain and functional performance in knee OA. LLLT has been used on different points on knee joint and also applied on acupuncture points of the knee joints. Different outcomes were used to assess LLLT effectiveness including pain, ROM and even different biomarkers. This study is going to use LLLT on different particular joint points of knee and also acupuncture points of the knee joint and compare the outcomes. This study will present evidence for the clinicians to use LLLT on either the particular joint points or acupuncture points for better clinical outcomes.

Conditions

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Knee Osteoarthritis

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Interventional study to compare the effectiveness of low level laser therapy on two groups of points of irradiation in knee OA grade III. One group of points involves 6-7 particular points on tibiofemoral and patellofemoral joints. Other group involves the 6-7 particular acupuncture points which have been previously used in a study. Outcomes will indicate that which group irradiation will produce better therapeutic results.
Primary Study Purpose

TREATMENT

Blinding Strategy

SINGLE

Outcome Assessors
Person assessing the outcomes will have no knowledge that patient received laser therapy on which points of knee area.

Study Groups

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Particular joint point group

This group will receive laser irradiation on 6-7 particular points including 4-5 on tibiofemoral and 2 on patellofemoral joint.

Group Type EXPERIMENTAL

Low level laser therapy

Intervention Type DEVICE

Omega XP is the particular device producing low level laser therapy and has been in use for therapeutic purposes to treat different musculoskeletal conditions.

Acupuncture points group

This group will receive laser irradiation on 6-7 particular acupuncture points which have been previously used in another study and or identified in literature.

Group Type EXPERIMENTAL

Low level laser therapy

Intervention Type DEVICE

Omega XP is the particular device producing low level laser therapy and has been in use for therapeutic purposes to treat different musculoskeletal conditions.

Interventions

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Low level laser therapy

Omega XP is the particular device producing low level laser therapy and has been in use for therapeutic purposes to treat different musculoskeletal conditions.

Intervention Type DEVICE

Other Intervention Names

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Cold laser therapy

Eligibility Criteria

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Inclusion Criteria

* Pain in the knee joint ( minimum 30/100 on VAS )
* Kellgren-Lawrence Grade III knee OA
* ACR criteria for knee OA with radiological findings including ;

* age 35 and above
* joint crepitus
* less than 30 minutes of morning stiffness

Exclusion Criteria

* Knee OA grade other than III.
* Any contraindication of LLLT including;

* pregnancy
* carcinoma involving knee area
* Steroids and NSAIDS use
Minimum Eligible Age

35 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Universiti Teknologi Malaysia

OTHER

Sponsor Role lead

Responsible Party

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Adnan Afzal

Principal Investigator

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Adnan Afzal, PhD

Role: PRINCIPAL_INVESTIGATOR

University of Technology Malaysia

Locations

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Central Park Teaching Hospital

Lahore, Punjab Province, Pakistan

Site Status RECRUITING

Countries

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Pakistan

Central Contacts

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Adnan Afzal, PhD*

Role: CONTACT

+ 92 3085389670

Muhammad Hanif Ramlee, PhD

Role: CONTACT

+60 75558480

Facility Contacts

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Maryam, MBBS

Role: primary

+92 3014789648

References

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Hegedus B, Viharos L, Gervain M, Galfi M. The effect of low-level laser in knee osteoarthritis: a double-blind, randomized, placebo-controlled trial. Photomed Laser Surg. 2009 Aug;27(4):577-84. doi: 10.1089/pho.2008.2297.

Reference Type BACKGROUND
PMID: 19530911 (View on PubMed)

Bjordal JM, Couppe C, Chow RT, Tuner J, Ljunggren EA. A systematic review of low level laser therapy with location-specific doses for pain from chronic joint disorders. Aust J Physiother. 2003;49(2):107-16. doi: 10.1016/s0004-9514(14)60127-6.

Reference Type BACKGROUND
PMID: 12775206 (View on PubMed)

Al Rashoud AS, Abboud RJ, Wang W, Wigderowitz C. Efficacy of low-level laser therapy applied at acupuncture points in knee osteoarthritis: a randomised double-blind comparative trial. Physiotherapy. 2014 Sep;100(3):242-8. doi: 10.1016/j.physio.2013.09.007. Epub 2013 Nov 15.

Reference Type BACKGROUND
PMID: 24418801 (View on PubMed)

Other Identifiers

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Admin/GDEC/276/20

Identifier Type: -

Identifier Source: org_study_id

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