Minimally Invasive Versus Open Surgery for PHC

NCT ID: NCT05402618

Last Updated: 2022-06-02

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

783 participants

Study Classification

OBSERVATIONAL

Study Start Date

2018-05-01

Study Completion Date

2022-04-01

Brief Summary

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Brief Summary: This is a multicentric, retrospective, real-world study to investigate the surgical outcomes of minimally invasive surgery compared with open surgery for Perihilar Cholangiocarcinoma (PHC), with the perioperative characteristics and long-term overall survival being compared. We aimed to find out whether the minimally invasive surgery is safe or feasible for PHC. And we also want to find out patients with what kind of characteristic can be benefit from the minimally invasive surgery compared with the open approach.

Detailed Description

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Conditions

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Perihilar Cholangiocarcinoma

Study Design

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Observational Model Type

COHORT

Study Time Perspective

RETROSPECTIVE

Study Groups

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minimally invasive surgery

No intervention

Intervention Type OTHER

This is an observational study without any intervention.

open surgery

No intervention

Intervention Type OTHER

This is an observational study without any intervention.

Interventions

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No intervention

This is an observational study without any intervention.

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

Histologically confirmed PHC.

Exclusion Criteria

1. Peritoneal seeding or metastasis to the liver, para-aortic lymph nodes, or distant sites;
2. Non-adenocarcinoma histology;
3. Incomplete clinical data.
Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Renyi Qin

OTHER

Sponsor Role lead

Responsible Party

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Renyi Qin

Professor

Responsibility Role SPONSOR_INVESTIGATOR

Locations

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Department of Biliary and Pancreatic Surgery, Tongji Hospital, Affiliated Tongji Medical College, Huazhong University of Science and Technology

Wuhan, Hubei, China

Site Status

Countries

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China

References

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Wang M, Qin T, Zhang H, Li J, Deng X, Zhang Y, Zhao W, Fan Y, Li D, Chen X, Feng Y, Zhu S, Xing Z, Yu G, Xu J, Xie J, Dou C, Ma H, Liu G, Shao Y, Chen W, Liu J, Liu J, Yin X, Qin R. Laparoscopic versus open surgery for perihilar cholangiocarcinoma: a multicenter propensity score analysis of short- term outcomes. BMC Cancer. 2023 May 3;23(1):394. doi: 10.1186/s12885-023-10783-9.

Reference Type DERIVED
PMID: 37138243 (View on PubMed)

Other Identifiers

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TJDBPS10

Identifier Type: -

Identifier Source: org_study_id

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