The Effect of the 3/7 vs 3X9 Method in Resistance Training on Metabolic Stress in Cardiac Rehabilitation

NCT ID: NCT05391620

Last Updated: 2024-02-14

Basic Information

• Recruitment Status: COMPLETED
• Clinical Phase: NA
• Total Enrollment: 25 participants
• Study Classification: INTERVENTIONAL
• Study Start Date: 2022-02-22
• Study Completion Date: 2022-10-25

Brief Summary

The study proposes to measure the effect of resitance training (RT) (3/7 method) on biological markers of muscle hypertrophy in a cardiac population.

3/7 method consisting of five sets of an increasing number of repetitions (3 to 7) during successive sets and brief inter-set intervals (15 s). This method is compare to 3X9 method, 3 series of 9 repetitions with inter-set (1min).The training exercise consisted of contraction on machine (leg press, triceps press, leg curl, traction, leg extension) with load of ~ 70% of one repetition maximal (1RM).

Before these trainings all subject perform HIIT on bicycles (2 min high intensity (80% Wmax) and 2 min low intensity (50% Wmax) during 30 minutes.

The investigators collect blood sample before exercice, after HIIT and after RT.

It is randomized cross-over study.

Detailed Description

The subjects come on two different days minimum 2 days and maximum 10 days between the two tests. They were instructed to avoid exercise the day before they participated in the study.

The investigators collect blood 2 minutes after endurance training (HIIT) and 2 min after RT training.

Conditions

Heart Failure; Resistance Training; Coronary Artery Disease

Study Design

• Allocation Method: RANDOMIZED
• Intervention Model: CROSSOVER
• Primary Study Purpose: OTHER
• Blinding Strategy: DOUBLE

Study Groups

CAD group

Coronary artery diseases

Group Type: EXPERIMENTAL

Cardiac rehabilitation with 3/7 method

Intervention Type: OTHER

HIIT ( 2 min 80% wmax: 2 min 50% wmax) during 30 minutes 3/7 method 3 rep (15 sec of rest), 4 rep (15 sec), 5 rep (15 sec), 6 rep (15 sec), 7 rep. (total volume : 25 repetitions) at 70 of 1 repetition Leg press, Dips Press, Leg curl, Traction and Leg extension.

1 minute between each machine is planned.

Cardiac rehabilitation with 3X9 method

Intervention Type: OTHER

HIIT ( 2 min 80% wmax: 2 min 50% wmax) during 30 minutes 3X9 method 9 rep 1 minute of rest, 9 rep (1 min) and 9 rep (total volume : 27 repetitions) at 70 of 1 repetition Leg press, Dips Press, Leg curl, Traction and Leg extension.

1 minute between each machine is planned

HFrEF group

Heart Failure with reduced Ejection Fraction

Group Type: EXPERIMENTAL

Cardiac rehabilitation with 3/7 method

Intervention Type: OTHER

HIIT ( 2 min 80% wmax: 2 min 50% wmax) during 30 minutes 3/7 method 3 rep (15 sec of rest), 4 rep (15 sec), 5 rep (15 sec), 6 rep (15 sec), 7 rep. (total volume : 25 repetitions) at 70 of 1 repetition Leg press, Dips Press, Leg curl, Traction and Leg extension.

1 minute between each machine is planned.

Cardiac rehabilitation with 3X9 method

Intervention Type: OTHER

HIIT ( 2 min 80% wmax: 2 min 50% wmax) during 30 minutes 3X9 method 9 rep 1 minute of rest, 9 rep (1 min) and 9 rep (total volume : 27 repetitions) at 70 of 1 repetition Leg press, Dips Press, Leg curl, Traction and Leg extension.

1 minute between each machine is planned

Interventions

Cardiac rehabilitation with 3/7 method

HIIT ( 2 min 80% wmax: 2 min 50% wmax) during 30 minutes 3/7 method 3 rep (15 sec of rest), 4 rep (15 sec), 5 rep (15 sec), 6 rep (15 sec), 7 rep. (total volume : 25 repetitions) at 70 of 1 repetition Leg press, Dips Press, Leg curl, Traction and Leg extension.

1 minute between each machine is planned.

Intervention Type: OTHER

Cardiac rehabilitation with 3X9 method

HIIT ( 2 min 80% wmax: 2 min 50% wmax) during 30 minutes 3X9 method 9 rep 1 minute of rest, 9 rep (1 min) and 9 rep (total volume : 27 repetitions) at 70 of 1 repetition Leg press, Dips Press, Leg curl, Traction and Leg extension.

1 minute between each machine is planned

Intervention Type: OTHER

Other Intervention Names

3/7 method; 3X9 method

Eligibility Criteria

Inclusion Criteria

• Clinical Coronary artery diseases
• Heart failure with reduced ejection fraction

Exclusion Criteria

• angina
• acutely decompensated heart failure
• electrocardiographic evidence of ischemia
• significant valvular disease
• orthopedic/neurologic disorders that limited exercise

• Minimum Eligible Age: 18 Years
• Eligible Sex: MALE
• Accepts Healthy Volunteers: No

Sponsors

Université Libre de Bruxelles

OTHER

Sponsor Role: lead

Responsible Party

Alexis Gillet

Principal Investigator

Responsibility Role: PRINCIPAL_INVESTIGATOR

Principal Investigators

Philippe van de borne, Professor

Role: STUDY_DIRECTOR

Erasme University Hospital, Université Libre de Bruxelles, Brussels, Belgium

Locations

Erasme Hospital

Brussels, , Belgium

Countries

Belgium

References

Mang ZA, Realzola RA, Ducharme J, Bellissimo GF, Beam JR, Mermier C, de Castro Magalhaes F, Kravitz L, Amorim FT. The effect of repetition tempo on cardiovascular and metabolic stress when time under tension is matched during lower body exercise. Eur J Appl Physiol. 2022 Jun;122(6):1485-1495. doi: 10.1007/s00421-022-04941-3. Epub 2022 Apr 8.

Reference Type: BACKGROUND

PMID: 35394146 (View on PubMed)

Other Identifiers

2020276

Identifier Type: -

Identifier Source: org_study_id