Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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ACTIVE_NOT_RECRUITING
NA
10 participants
INTERVENTIONAL
2022-08-01
2027-01-31
Brief Summary
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Detailed Description
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Conditions
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Study Design
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RANDOMIZED
CROSSOVER
TREATMENT
NONE
Study Groups
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Potassium citrate
Potassium citrate
7 days potassium citrate followed by 24 hour urine collection
Crystal light
Crystal light
7 days crystal light followed by 24 hour urine collection
Crystal light + potassium citrate
Potassium citrate + crystal light
7 days potassium citrate + crystal light followed by 24 hour urine collection
Interventions
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Potassium citrate
7 days potassium citrate followed by 24 hour urine collection
Crystal light
7 days crystal light followed by 24 hour urine collection
Potassium citrate + crystal light
7 days potassium citrate + crystal light followed by 24 hour urine collection
Eligibility Criteria
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Inclusion Criteria
2. Willing to follow experimental protocol
3. Willing to complete 24-hour urine collections (three total)
4. Willing to sign the informed consent form
5. Completed Litholink Collection with blood work with results
a. hypocitraturia OR aciduria i. Hypocitraturics must meet definition of \< 450 mg/day for men \< 550 mg/day for women.
b. Low urine pH must be less than 5.6 c. potassium, BUN, creatinine, eGFR and hemoglobin A1c within normal limits
Exclusion Criteria
2. Patients with hyperkalemia, uncontrolled diabetes, chronic kidney disease, adrenal insufficiency, delayed gastric emptying (or drug induced delayed gastric emptying), peptic ulcer disease, or active UTI
3. Patients with distal renal tubular acidosis or medication induced RTA (e.g. carbonic anhydrase inhibitor, topiramate)
4. Members of vulnerable patient populations
5. Allergies to ingredients in crystal light
6. Patients lacking decisional capacity
18 Years
80 Years
ALL
No
Sponsors
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Northwestern University
OTHER
Responsible Party
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Amy Krambeck
Director of the Endourology/Stone Division
Locations
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Northwestern University
Chicago, Illinois, United States
Countries
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Other Identifiers
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STU00216084
Identifier Type: -
Identifier Source: org_study_id
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