Rural South and Southeast Asia Household Health Survey

NCT ID: NCT05389540

Last Updated: 2024-02-28

Basic Information

• Recruitment Status: COMPLETED
• Total Enrollment: 4747 participants
• Study Classification: OBSERVATIONAL
• Study Start Date: 2022-10-03
• Study Completion Date: 2023-12-10

Brief Summary

A cross-sectional household survey with two-stage cluster-randomized sampling. This cross-sectional household survey design to recruit a random sample of households that is representative for each of the study sites. From the selected households, all consenting, household members will be included in the study.

This study is funded by the UK Wellcome Trust. The grant reference number is 215604/Z/19/Z

Detailed Description

371 households will be randomly selected from each site in Bangladesh, Cambodia, Myanmar, and Thailand. Assuming each household has an average of 4.5 members and all members will be sampled, 1500 participants will be recruited per site. This sample size allows for the overall prevalence estimation of key survey indicators with 95% confidence and 5% degree of precision.

The survey components include questionnaire interview, physical examination, blood sample collection, and point of care (PoC) tests. The questionnaire interview will collect information on household characteristics, members' disability, presence or history of disease, risk factors, self-perceived quality of life, and health seeking behaviour. For women, questions about reproductive health and antenatal care, and for young children, vaccination coverage and achievement of child development goals, will also be assessed.

For physical examinations, tympanic temperature, weight and height will be measured in all household members, mid-upper arm circumference in young children, and blood pressure in adults. Blood sample will be collected from all participants aged 6 months and above. Venous blood samples will be collected from participants aged 5 years and older, and dried blood spot will be collected from children under 5 years. Samples will be shipped to a central laboratory and analysed. Haemoglobin PoC will be administered to all participants.

All data will be collected directly on an electronic case report form using tablets, and uploaded to an electronic database.

Conditions

Noncommunicable Disease; Infections; Risk Factors; Health Status

Study Design

• Observational Model Type: ECOLOGIC_OR_COMMUNITY
• Study Time Perspective: CROSS_SECTIONAL

Study Groups

members of selected households at the time of survey

371 households will be randomly selected from each site in Bangladesh, Cambodia, Myanmar, and Thailand. Assuming each household has an average of 4.5 members and all members will be sampled, 1500 participants will be recruited per site.

No interventions assigned to this group

Eligibility Criteria

Inclusion Criteria

• All members of the selected households at the time of the survey; and able to provide informed consent.

Exclusion Criteria

• Adults or children whose parent/guardian/ caretaker are unable or unwilling to provide informed consent.

• Eligible Sex: ALL
• Accepts Healthy Volunteers: Yes

Sponsors

Mahidol Oxford Tropical Medicine Research Unit

OTHER

Sponsor Role: collaborator

Chiang Rai Clinical Research Unit, Thailand

UNKNOWN

Sponsor Role: collaborator

Myanmar Oxford Clinical Research Unit, Yangon, Myanmar

UNKNOWN

Sponsor Role: collaborator

Bangladesh Rural Advancement Committee, Dhaka, Bangladesh

UNKNOWN

Sponsor Role: collaborator

Cambodia Action for Health Development (AHEAD)

UNKNOWN

Sponsor Role: collaborator

University of Oxford

OTHER

Sponsor Role: lead

Responsible Party

Responsibility Role: SPONSOR

Principal Investigators

Yoel Lubell, Professor

Role: PRINCIPAL_INVESTIGATOR

Mahidol Oxford Tropical Medicine Research Unit

Thomas Peto, PhD

Role: PRINCIPAL_INVESTIGATOR

Mahidol Oxford Tropical Medicine Research Unit

Locations

BangladeshBuilding Resources Across Communities (BRAC)

Dhaka, , Bangladesh

Medical Action Myanmar (MAM)

Yangon, , Burma

Cambodia Action for Health Development (AHEAD)

Battambang, , Cambodia

Chiangrai Clinical Research Unit (CCRU)

Chiang Rai, , Thailand

Countries

Bangladesh; Burma; Cambodia; Thailand

References

Chandna A, Chew R, Shwe Nwe Htun N, Peto TJ, Zhang M, Liverani M, Brummaier T, Phommasone K, Perrone C, Pyae Phyo A, Sattabongkot J, Roobsoong W, Nguitragool W, Sen A, Ibna Zaman S, Sandar Zaw A, Batty E, Waithira N, Abdad MY, Blacksell SD, Bodhidatta L, Callery JJ, Fagnark W, Huangsuranun W, Islam S, Lertcharoenchoke S, Lohavittayavikant S, Mukaka M, Moul V, Kumer Neogi A, Nedsuwan S, Pongvongsa T, Ponsap P, Richard-Greenblatt M, Schilling WHK, Thaipadungpanit J, Tripura R, Dondorp AM, Mayxay M, White NJ, Nosten F, Smithuis F, Ashley EA, Maude RJ, Day NPJ, Lubell Y. Defining the burden of febrile illness in rural South and Southeast Asia: an open letter to announce the launch of the Rural Febrile Illness project. Wellcome Open Res. 2022 Mar 10;6:64. doi: 10.12688/wellcomeopenres.16393.2. eCollection 2021.

Reference Type: BACKGROUND

PMID: 34017924 (View on PubMed)

Zhang M, Htun NSN, Islam S, Sen A, Islam A, Neogi AK, Tripura R, Dysoley L, Perrone C, Chew R, Batty EM, Thongpiam W, Wongsantichon J, Menggred C, Zaman SI, Waithira N, Blacksell S, Liverani M, Lee S, Maude RJ, Day NPJ, Lubell Y, Peto TJ. Defining the hidden burden of disease in rural communities in Bangladesh, Cambodia and Thailand: a cross-sectional household health survey protocol. BMJ Open. 2024 Mar 23;14(3):e081079. doi: 10.1136/bmjopen-2023-081079.

Reference Type: DERIVED

PMID: 38521526 (View on PubMed)

Related Links

https://seactn.org/

Related Info

Other Identifiers

HCR21013

Identifier Type: -

Identifier Source: org_study_id