Investigation of Endemic and Emerging Diseases in Populations of Homeless Households in Marseille.

NCT ID: NCT02819128

Last Updated: 2023-04-21

Basic Information

• Recruitment Status: COMPLETED
• Clinical Phase: NA
• Total Enrollment: 722 participants
• Study Classification: INTERVENTIONAL
• Study Start Date: 2014-01-25
• Study Completion Date: 2022-10-26

Brief Summary

Hypothesis:

Homeless people have infections not diagnosed with a potential impact on their health status.

Main Purpose: Improve the etiological diagnosis of endemic and/or emerging pathologies among homeless people.

Detailed Description

In Marseilles, the population of homeless is estimated at 1500 individuals, including 800 usually sleeping in the street, 600 in foster homes and a hundred in the structures of care. The precarious living conditions of homeless persons promote the emergence or re-emergence of many communicable infectious diseases homeless people whose symptoms are often overlooked by the subject and rarely established etiologic diagnosis.

Among these diseases, frequently described in the literature are infestation by lice and infectious diseases that they transmit (Bartonella quintana), skin infections, hepatitis E and C and finally the infection with Tropheryma Whipplei. In this study we propose to systematically in homeless subject an etiological diagnosis of pathogens at the origin of these diseases (i) to improve knowledge (ii) to improve their management, (iii) to limit the contagion.

Conditions

Endemic and Emerging Diseases in Populations of Homeless

Study Design

• Allocation Method: NA
• Intervention Model: SINGLE_GROUP
• Primary Study Purpose: DIAGNOSTIC
• Blinding Strategy: NONE

Study Groups

Homeless people

Populations of homeless households in Marseille.

Group Type: OTHER

Swabs skin, pharyngeal, and blood sample

Intervention Type: OTHER

Collection of one blood sample with a volume of 10 mL (2 tubes of blood 5 mL ) and 2 swabs ( throat and skin ).

Collection of body lice

Intervention Type: OTHER

For the subjects infested with body lice , if they want, their underwear will be recovered and sent to the laboratory to measure the resistance to permethrin.

Interventions

Swabs skin, pharyngeal, and blood sample

Collection of one blood sample with a volume of 10 mL (2 tubes of blood 5 mL ) and 2 swabs ( throat and skin ).

Intervention Type: OTHER

Collection of body lice

For the subjects infested with body lice , if they want, their underwear will be recovered and sent to the laboratory to measure the resistance to permethrin.

Intervention Type: OTHER

Eligibility Criteria

Inclusion Criteria

• Homeless Subject on the day of the study in one of two shelters for homeless Marseille ( Madrague City and Forbin )
• Major subject ( > or equal to 18 years)
• Freely about having signed the written informed consent,
• About affiliated with a social security scheme

Exclusion Criteria

• Minor Subjects ( < 18 years )
• Major subject under guardianship (L. 1121-8 )
• Subject privated of freedom or under court order (L. 1121-6 )
• Subject refusing to sign the informed consent form ,
• Subject not affiliated with a social security insurance
• Pregnant women , parturient or nursing (L. 1121-7 ) .

• Minimum Eligible Age: 18 Years
• Eligible Sex: ALL
• Accepts Healthy Volunteers: No

Sponsors

Assistance Publique Hopitaux De Marseille

OTHER

Sponsor Role: lead

Responsible Party

Responsibility Role: SPONSOR

Principal Investigators

Philippe BROUQUI, Pr

Role: PRINCIPAL_INVESTIGATOR

Assistance Publique - Hôpitaux de Marseille

Locations

Assistance Publique Hopitaux de Marseille

Marseille, , France

Countries

France

Other Identifiers

2013-44

Identifier Type: -

Identifier Source: org_study_id