Relationship of PNI and Clinical Outcome in Patients Undergoing Brain Tumor Surgery

NCT ID: NCT05373836

Last Updated: 2024-04-19

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

NOT_YET_RECRUITING

Total Enrollment

5000 participants

Study Classification

OBSERVATIONAL

Study Start Date

2024-12-12

Study Completion Date

2025-12-31

Brief Summary

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There are several predictors of clinical outcome in patients undergoing brain tumor surgery. Among those, nutritional parameters and calculated nutritional index are known to have ability to predict mortality and clinical outcomes in some patients with brain tumor. However, there are lack of consistent results on predictability of nutritional index and clinical outcome in patients undergoing brain tumor surgery.

Detailed Description

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In this retrospective study, we evaluated the relationship between prognostic nutritional index, which was calculated from laboratory parameters, and clinical outcome including mortality in patients undergoing brain tumor surgery.

Conditions

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Clinical Outcome

Study Design

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Observational Model Type

COHORT

Study Time Perspective

RETROSPECTIVE

Study Groups

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brain tumor surgery

adult patients undergoing brain tumor surgery

prognostic nutritional index calculated from laboratory parameters

Intervention Type DIAGNOSTIC_TEST

Calculated nutritional index using laboratory results of serum albumin, lymphocyte count, and cholesterol

Interventions

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prognostic nutritional index calculated from laboratory parameters

Calculated nutritional index using laboratory results of serum albumin, lymphocyte count, and cholesterol

Intervention Type DIAGNOSTIC_TEST

Eligibility Criteria

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Inclusion Criteria

* adult patients undergoing brain tumor surgery at Seoul National University Hospital, South Korea

Exclusion Criteria

* Lack of results of laboratory parameters, such as serum albumin, lymphocyte count, cholesterol
* Lack of data on clinical outcome, including mortality, acute kidney injury, renal replacement therapy, length of hospital stay, and other major adverse outcome
Minimum Eligible Age

20 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Seoul National University Hospital

OTHER

Sponsor Role lead

Responsible Party

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Youn Joung Cho, MD, PhD

Clinical Associate Professor

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Youn Joung Cho, MD, PhD

Role: PRINCIPAL_INVESTIGATOR

Seoul National University Hospital

Central Contacts

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Youn Joung Cho, MD, PhD

Role: CONTACT

+82220722467

Other Identifiers

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PNI_Brain tumor

Identifier Type: -

Identifier Source: org_study_id

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