Association Between Prescription of Antidepressants and Delirium in the Elderly : Analysis From the World Health Organization Global Database
NCT ID: NCT05356078
Last Updated: 2022-05-02
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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UNKNOWN
10000 participants
OBSERVATIONAL
2022-01-03
2022-06-03
Brief Summary
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Antidepressants are widely prescribed in the elderly because of the frequency of anxiety-depressive symptoms in this population, where there are high pharmacokinetic and pharmacodynamic variability.
However, the association between antidepressants and the risk of delirium remains poorly understood.
Based on the analysis from the World Health Organization global database, the main objective of this study is to investigate the association between the different classes of antidepressants and the occurrence of the " delirium " event reported in the database.
A disproportionality analysis will be performed. It will aim to assess whether some classes of antidepressants, and within these classes some molecules, are associated with a greater risk of delirium.
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Detailed Description
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Conditions
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Study Design
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COHORT
RETROSPECTIVE
Interventions
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Antidepressant
"Delirium" event reported in the World Health Organization global database in subjects aged over 65 years taking antidepressants, comparative analysis by antidepressant class
Eligibility Criteria
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Inclusion Criteria
* taking antidepressants
* to have presented delirium
Exclusion Criteria
65 Years
120 Years
ALL
No
Sponsors
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University Hospital, Caen
OTHER
Responsible Party
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Locations
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Caen University Hospital, Department of Pharmacology
Caen, Normandy, France
Countries
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Other Identifiers
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Pharmaco20220103
Identifier Type: -
Identifier Source: org_study_id
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