Comparison of Fetal Thymus Volumes of Pregnant Women With In Vitro Fertilization (IVF) and Spontaneous Pregnant Women.

NCT ID: NCT05347433

Last Updated: 2022-04-26

Basic Information

• Recruitment Status: COMPLETED
• Total Enrollment: 74 participants
• Study Classification: OBSERVATIONAL
• Study Start Date: 2019-07-09
• Study Completion Date: 2021-08-01

Brief Summary

The purpose of the study was to compare the fetal thymus volumes of 18-24-week pregnant women with In Vitro Fertilization (IVF) and spontaneous pregnant women.

Conditions

Healthy

Study Design

• Observational Model Type: CASE_CONTROL
• Study Time Perspective: CROSS_SECTIONAL

Study Groups

Tube baby pregnancy group

18-24-week pregnant women with in vitro fertilization

No interventions assigned to this group

Spontaneous pregnancy group

18-24-week pregnant women with spontaneous

No interventions assigned to this group

Eligibility Criteria

Inclusion Criteria

• pregnant between 18-24 weeks
• had no complaints
• between the ages of 18-35
• conceived with in vitro fertilization or spontaneously

Exclusion Criteria

• history of endocrinopathies (including diabetes mellitus, hyperprolactinemia, Cushing's disease, and congenital adrenal hyperplasia), systemic diseases (e.g. asthma), collagen disorder, hypercholesterolemia, sickle cell anemia, or neoplasm,
• those who had a history of coronary artery disease, angina, or myocardial infarction, or a history of hypertension, coronary arteritis, and electrocardiographic changes that suggest any known history of vascular, infectious, or inflammatory disease, maternal autoimmune disease,
• use of any drugs other than those used for IVF (e.g. insulin sensitizing drugs, oral contraceptives, antiandrogens, statins, aspirin, and corticosteroids) in the 3 months before the pregnancy,
• multiple pregnancy,
• present cigarette and alcohol use,
• abnormal renal, hepatic, and thyroid function test results;
• refusing to participate in the study,
• abnormal fetal findings (fetal anomaly, increased nape transparency, first-second trimester screening test disorder),
• cases who did not meet the criteria for pregnancy after the first tube treatment (ICSI-ET) because of normoresponder, unexplained infertility, or male factor

• Minimum Eligible Age: 18 Years
• Maximum Eligible Age: 34 Years
• Eligible Sex: FEMALE
• Accepts Healthy Volunteers: Yes

Sponsors

Karadeniz Technical University

OTHER

Sponsor Role: lead

Responsible Party

Nurgül Selin KAYA

doctor

Responsibility Role: PRINCIPAL_INVESTIGATOR

Locations

Karadeniz Technical University

Trabzon, , Turkey (Türkiye)

Countries

Turkey (Türkiye)

Other Identifiers

2019/205

Identifier Type: -

Identifier Source: org_study_id