Intravenous Magnesium Sulfate Vs Placebo to Treat Non -Traumatic Acute Headaches in the Emergency Department
NCT ID: NCT05325580
Last Updated: 2024-02-28
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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RECRUITING
PHASE3
424 participants
INTERVENTIONAL
2021-12-01
2026-12-30
Brief Summary
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Detailed Description
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Conditions
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Study Design
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RANDOMIZED
PARALLEL
TREATMENT
TRIPLE
Study Groups
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Placebo Group
1g paracetamol + 20 min infusion of 150ml of saline serum
Magnesium sulfate
magnesium group 1g paracetamol + 20 min infusion of 2 g magnesium in 150 ml of saline serum and Placebo Group
1g paracetamol + 20 min infusion of 150 ml of saline serum
magnesium group
1g paracetamol + 20 min infusion of 2g magnesium in 150 ml of serum saline
Magnesium sulfate
magnesium group 1g paracetamol + 20 min infusion of 2 g magnesium in 150 ml of saline serum and Placebo Group
1g paracetamol + 20 min infusion of 150 ml of saline serum
Interventions
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Magnesium sulfate
magnesium group 1g paracetamol + 20 min infusion of 2 g magnesium in 150 ml of saline serum and Placebo Group
1g paracetamol + 20 min infusion of 150 ml of saline serum
Other Intervention Names
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Eligibility Criteria
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Inclusion Criteria
* age \>18 years
* Acute non-traumatic acute headaches
* patients treated in ED
* Magnesium sulfate and aspirin administered intravenously (IV)
Exclusion Criteria
* Renal disorder with a low glomerular filtration rate (\<60 ml/min)
* Neuromuscular disorder
* Pregnant woman
* Contrindication
* Allergy to NSAID
* Traumatic Headache
* Chronic headache ( headache occurring at least 15 days per month for at least 3 months)
* Hemodynamic instability
18 Years
85 Years
ALL
No
Sponsors
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University of Monastir
OTHER
Responsible Party
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Pr. Semir Nouira
Pr.Semir Nouira chef of emergency deparment
Principal Investigators
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Semir Nouira, Professor
Role: PRINCIPAL_INVESTIGATOR
University of Monastir
Locations
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University of Monasrtir
Monastir, , Tunisia
Countries
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Central Contacts
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Facility Contacts
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Other Identifiers
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Emergency Monastir
Identifier Type: -
Identifier Source: org_study_id
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