Immuno-epidemiological and Socio-behavioral Evaluation of Release of Sterile Male Aedes Albopictus Mosquitoes on Human-vector Contacts
NCT ID: NCT05313126
Last Updated: 2022-04-06
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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UNKNOWN
NA
500 participants
INTERVENTIONAL
2021-11-09
2023-06-30
Brief Summary
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1. ExpAlbo Biomarker (Exposure to the Aedes albopictus mosquito): This component concerns the epidemiological evaluation of the effectiveness of the release of sterile male mosquitoes on the level of exposure of individuals to the bites of the tiger mosquito through the use of a new immunological biomarker of the human-vector contact, developed over the past 20 years by the IRD-MIVEGEC team. Indeed, when a person is bitten by a mosquito, he or she develops a defence reaction, called an immune reaction, against the mosquito's saliva. The main objective of this study is to measure this immune response, and more specifically the antibody response specifically directed against compounds (peptide = small fragment of a protein) in mosquito saliva, and to determine whether this anti-saliva antibody response, and therefore exposure to mosquito bites, decreases when the mosquito control strategy is applied.
2. CAPAlbo Questionnaire: This component is concerned with assessing the impact of sterile male mosquito releases on perceptions and practices related to exposure to Aedes albopictus based on population-based questionnaire surveys. The main objective of these surveys is to determine whether changes in objective exposure to Aedes albopictus mosquitoes are associated with changes in the perception of the nuisance and in the lifestyle habits of respondents, particularly those related to the prevention of mosquito bites (such as the use of repellents or mosquito nets).
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Detailed Description
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Conditions
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Study Design
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NON_RANDOMIZED
PARALLEL
PREVENTION
NONE
Study Groups
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sterile male Aedes albopictus-exposed
Sterile male Aedes albopictus are released in the area.
sterile insect technique (TIS)
Sterile male Aedes albopictus mosquitos are released in the area/neighborhood
control
Sterile male Aedes albopictus are not released in the area.
No interventions assigned to this group
Interventions
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sterile insect technique (TIS)
Sterile male Aedes albopictus mosquitos are released in the area/neighborhood
Eligibility Criteria
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Inclusion Criteria
* To speak French
18 Years
ALL
Yes
Sponsors
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Institut de Recherche pour le Developpement
OTHER_GOV
Responsible Party
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Locations
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population générale (quartier Duparc (Sainte Marie) et Quartier Bois rouge)
La Réunion, , France
Countries
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Central Contacts
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Facility Contacts
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Other Identifiers
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2020-A03558-31
Identifier Type: -
Identifier Source: org_study_id
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