A Prospective Clinical Study to Assess the Clinical Utility of Turbidity in Patients Using In-Home Peritoneal Dialysis

NCT ID: NCT05285436

Last Updated: 2023-09-21

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Clinical Phase

NA

Total Enrollment

314 participants

Study Classification

INTERVENTIONAL

Study Start Date

2022-03-16

Study Completion Date

2024-12-31

Brief Summary

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This study aims to determine if the CloudCath device can detect infections related to peritoneal dialysis (peritonitis) as fast or faster than the current standard methods used by patients and doctors to detect such infections.

Detailed Description

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This study will evaluate the safety and effectiveness of the CloudCath System to detect the onset of peritonitis as compared to standard of care.

Study Participants will connect the CloudCath System to their home peritoneal dialysis unit and the CloudCath System will analyze the effluent dialysis solution for changes associated with peritonitis. The system will alert the participant and healthcare provider if it detects a possible infection so they can be formally diagnosed by their healthcare provider.

Following enrollment, Study Participants will use the CloudCath System for 12 continuous months.

Study results from the ACT study will be compared to the results of the CATCH Study (Protocol number CC-P-001; NCT04515498). In CATCH, the Study Participants used a CloudCath System; however, the notification capabilities (per the CloudCath System algorithm) were deactivated.

Conditions

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End Stage Renal Disease Peritoneal Dialysis-associated Peritonitis Peritonitis

Study Design

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Allocation Method

NA

Intervention Model

SINGLE_GROUP

All study participants receive a CloudCath Device and use it at home adjunctively to their regular peritoneal dialysis system.
Primary Study Purpose

DIAGNOSTIC

Blinding Strategy

NONE

Study Groups

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CloudCath detection

Active monitoring of dialysate effluent by the CloudCath System.

Group Type EXPERIMENTAL

CloudCath System

Intervention Type DEVICE

The CloudCath System enables drainage and measures turbidity, reported as a numeric score, in peritoneal dialysate effluent.

Interventions

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CloudCath System

The CloudCath System enables drainage and measures turbidity, reported as a numeric score, in peritoneal dialysate effluent.

Intervention Type DEVICE

Eligibility Criteria

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Inclusion Criteria

* currently using peritoneal dialysis
* provides informed consent
* willing to comply with the requirements of the study
* has cellular data coverage at home

Exclusion Criteria

* active or history of cancer requiring chemotherapy within prior 6 months
* signs or symptoms of an active infection within 14 days prior to enrollment
* peritonitis diagnosis within 30 days prior to enrollment
* participating in another investigational device or drug study that may potentially affect study results
* other medical, social or psychological problems that, in the opinion of the investigator, exclude the study participant from the study
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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CloudCath

INDUSTRY

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Glenn Chertow, MD

Role: STUDY_DIRECTOR

Stanford University

Locations

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Dialysis Center of Western Massachusetts Llc

Chicopee, Massachusetts, United States

Site Status RECRUITING

Countries

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United States

Central Contacts

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Brian Fisher

Role: CONTACT

+1 (415) 651-3393

Concetta Carbonaro

Role: CONTACT

Facility Contacts

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Concetta Carbonaro

Role: primary

Other Identifiers

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CC-P-002

Identifier Type: -

Identifier Source: org_study_id

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