Dialysis Catheter Comparative Clinical Trial

NCT ID: NCT00526123

Last Updated: 2013-01-07

Study Results

Results available

Outcome measurements, participant flow, baseline characteristics, and adverse events have been published for this study.

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Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

599 participants

Study Classification

INTERVENTIONAL

Study Start Date

2007-09-30

Study Completion Date

2011-08-31

Brief Summary

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The purpose of this clinical trial is to compare the longevity of two dialysis catheters.

Detailed Description

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This study is a multi-center, randomized, prospective, open-label, clinical study comparing a conventional split-tip catheter and a symmetric tip catheter in subjects undergoing hemodialysis.

Conditions

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End Stage Renal Disease

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

SINGLE_GROUP

Primary Study Purpose

TREATMENT

Blinding Strategy

NONE

Study Groups

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1

symmetric tip catheter

Group Type ACTIVE_COMPARATOR

Symmetric Tip Catheter

Intervention Type DEVICE

Dialysis catheter

2

conventional split-tip catheter

Group Type ACTIVE_COMPARATOR

Conventional Split-tip Catheter

Intervention Type DEVICE

Dialysis Catheter

Interventions

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Symmetric Tip Catheter

Dialysis catheter

Intervention Type DEVICE

Conventional Split-tip Catheter

Dialysis Catheter

Intervention Type DEVICE

Eligibility Criteria

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Inclusion Criteria

* Subject must be 18 years of age or older.
* Subject must meet labeled indication for hemodialysis.
* Subject must have End Stage Renal Disease (ESRD).
* Subject must have a patent right or left internal jugular vein.
* Subject treatment plan must require chronic hemodialysis treatments 3 times per week for a minimum of 6 weeks.
* Subject must give written informed consent.

Exclusion Criteria

* Subjects who are concurrently enrolled in any Randomized Clinical Trial (RCT) or those that may enroll in a RCT during the course of the study, or subjects who have been previously randomized into this clinical study.
* Subjects with active infection at the time of study enrollment.
* Subjects with a known sensitivity to heparin, or previous incidence of heparin-induced thrombocytopenia.
* Subjects with uncontrolled abnormal coagulation parameters and are at additional risk for clotting or excessive bleeding.
* Subjects who are known or suspected to be pregnant at the time of study enrollment or plan to get pregnant during the study period.
* Subjects for whom performing dialysis at flow rates up to 450 mL/min would be contraindicated for any reason.
* Subject unable or unwilling to commit to follow-up visits and study procedures throughout the course of the study.
* Subjects who, in the opinion of the Investigators, are not appropriate candidates for the study based upon current or past medical history, or negative past experience with either of the study catheters.
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Tyco Healthcare Group

INDUSTRY

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Klemens B Meyer, MD

Role: PRINCIPAL_INVESTIGATOR

Locations

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Nephrology Associates, P.C.

Birmingham, Alabama, United States

Site Status

Southwest Kidney Institute

Phoenix, Arizona, United States

Site Status

Tufts Medical Center

Boston, Massachusetts, United States

Site Status

Massachusetts General Hospital

Boston, Massachusetts, United States

Site Status

SUNY Stony Brook Medical Center

Stony Brook, New York, United States

Site Status

Eastern Nephrology Associates

Greenville, North Carolina, United States

Site Status

Eastern Nephrology Associates

New Bern, North Carolina, United States

Site Status

Boice-Willis Clinic

Rocky Mount, North Carolina, United States

Site Status

Dialysis Access Group of Wake Forest University, LLC

Winston-Salem, North Carolina, United States

Site Status

Toledo Hospital

Toledo, Ohio, United States

Site Status

Temple University Hospital

Philadelphia, Pennsylvania, United States

Site Status

Nephrology Associates - Lankenau Hospital

Wynnewood, Pennsylvania, United States

Site Status

Columbia Nephrology Associates

Columbia, South Carolina, United States

Site Status

Medical College of Wisconsin

Milwaukee, Wisconsin, United States

Site Status

Countries

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United States

Other Identifiers

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341.26

Identifier Type: -

Identifier Source: org_study_id

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