Efficacy of a Dietary Ingredient Combination With Omega-3 for Joint Function

NCT ID: NCT05279573

Last Updated: 2022-12-28

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

130 participants

Study Classification

INTERVENTIONAL

Study Start Date

2022-02-14

Study Completion Date

2022-12-23

Brief Summary

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Randomized, controlled, double-blind intervention study of four parallel branches depending on the product consumed, to analyze the efficacy of an Omega-3 based product on the mobility and functionality of the evaluated joint.

Detailed Description

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The duration of the study will be 60 days (8 weeks). Each day they will have to consume the product under investigation. Subjects who meet the selection criteria will be randomized into each of the study groups (A, B, C o D, depending on the group in which they have been randomized). Each day the subjects will have to fill in a diary regarding pain and concomitant medication.

They will make a total of two visits to the research laboratory and will perform the tests pre-established in the protocol. In addition, a follow-up telephone call will be made after 30 days of consume. Subsequently, a statistical analysis will be performed with the variables measured in the study to obtain the results.

Conditions

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Joint Function Disorder

Keywords

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Omega-3

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

OTHER

Blinding Strategy

QUADRUPLE

Participants Caregivers Investigators Outcome Assessors

Study Groups

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Combination of Omega-3 based product and botanical ingredient

Consumption for 60 days. Subjects should consume two capsules in the morning and two capsules in the afternoon.

Group Type EXPERIMENTAL

Omega-3 and/or botanical ingredient

Intervention Type DIETARY_SUPPLEMENT

Consumption for 60 days. Subjects should consume two capsules in the morning and two capsules in the afternoon.

Omega-3 based product

Consumption for 60 days. Subjects should consume two capsules in the morning and two capsules in the afternoon.

Group Type EXPERIMENTAL

Omega-3 and/or botanical ingredient

Intervention Type DIETARY_SUPPLEMENT

Consumption for 60 days. Subjects should consume two capsules in the morning and two capsules in the afternoon.

Botanical ingredient

Consumption for 60 days. Subjects should consume two capsules in the morning and two capsules in the afternoon.

Group Type EXPERIMENTAL

Omega-3 and/or botanical ingredient

Intervention Type DIETARY_SUPPLEMENT

Consumption for 60 days. Subjects should consume two capsules in the morning and two capsules in the afternoon.

Control group

Consumption for 60 days. Subjects should consume two capsules in the morning and two capsules in the afternoon.

Group Type PLACEBO_COMPARATOR

Control product consumption

Intervention Type OTHER

Product with identical characteristics to the experimental product. Consumption for 60 days. Subjects should consume two capsules in the morning and two capsules in the afternoon.

Interventions

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Omega-3 and/or botanical ingredient

Consumption for 60 days. Subjects should consume two capsules in the morning and two capsules in the afternoon.

Intervention Type DIETARY_SUPPLEMENT

Control product consumption

Product with identical characteristics to the experimental product. Consumption for 60 days. Subjects should consume two capsules in the morning and two capsules in the afternoon.

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* Healthy adults (age: 40-75 YO).
* Subjects must have persistent knee pain with a baseline VAS pain assessment score of at least 30 mm.
* Subjects should not present narcotic drugs or steroidal anti-inflammatory drugs or immunosuppressants in their treatment.

Exclusion Criteria

* Serious or terminal illnesses.
* Subjects currently taking glucosamine, chondroitin sulfate, collagen or hyaluronic infiltrations or any supplement indicated for joint health.
* Subjects who are currently consuming or have consumed in the last two months any Omega-3 based supplement and/or supplement based on the botanical ingredient under investigation.
* Subjects with chronic inflammatory diseases that affect the musculoskeletal system (rheumatoid arthritis, gout, pseudo-gout, Paget's disease, chronic pain syndrome, etc.).
* Subjects with a body mass index above 32.
* Subjects with known allergy to any of the study components.
* Pregnant or lactating women.
* Inability to understand informed consent.
Minimum Eligible Age

40 Years

Maximum Eligible Age

75 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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Evonik Operations GmbH

UNKNOWN

Sponsor Role collaborator

Universidad Católica San Antonio de Murcia

OTHER

Sponsor Role lead

Responsible Party

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Francisco Javier López Román

Principal Investigator

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Fco Javier López Roman

Role: PRINCIPAL_INVESTIGATOR

Catholic University of Murcia

Locations

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Catholic University of Murcia

Murcia, , Spain

Site Status

Countries

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Spain

Other Identifiers

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UCAMCFE-00020

Identifier Type: -

Identifier Source: org_study_id