The Immune Response to Stroke

NCT ID: NCT05277129

Last Updated: 2022-03-14

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

RECRUITING

Total Enrollment

40 participants

Study Classification

OBSERVATIONAL

Study Start Date

2021-06-24

Study Completion Date

2029-06-06

Brief Summary

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Some patients develop cognitive decline after a stroke, but we don't always understand the mechanisms. It has been proposed that a proportion of the patients develop an autoimmune immune response, and that this could potentially explain the cognitive decline in some of the patients. The current study aims to investigate this hypothesis in a subgroup of patients with stroke.

Detailed Description

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Conditions

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Stroke, Acute Dementia

Study Design

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Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Study Groups

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Stroke patients

Analysis of post-stroke immune responses

Intervention Type OTHER

Analysis of immune responses in peripheral blood

Interventions

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Analysis of post-stroke immune responses

Analysis of immune responses in peripheral blood

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* Stroke \< 72 h
* Age \> 18 years

Exclusion Criteria

* Brain hemorrhage verified by CT or MRI scan
* Previous or present immunological disease or other serious comorbidity
* Ongoing immune respons after infection or vaccination \< 1 month
* Cognitive without ability to understand and/or give an informed consent to participate in the study
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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University of Oslo

OTHER

Sponsor Role lead

Responsible Party

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Andreas Lossius

Associate Professor

Responsibility Role PRINCIPAL_INVESTIGATOR

Locations

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Akershus University Hospital

Lørenskog, , Norway

Site Status RECRUITING

Countries

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Norway

Central Contacts

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Andreas Lossius, MD, PhD

Role: CONTACT

+47 930 68 515

Facility Contacts

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Andreas Lossius, MD, PhD

Role: primary

Other Identifiers

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2019/1252

Identifier Type: -

Identifier Source: org_study_id

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